In one of the key lectures at the EADV Congress 2025, Prof. Gallo presented fascinating findings on the interaction between the skin, gut and brain. His research revealed unknown pathways through which these organs communicate to influence systemic diseases. For example, he described a mechanism by which the adrenal hormone alters the infectious defence functions of skin cells.
Another study revealed how a molecule released by psoriasis can make LDL more dangerous, which is an important link to heart health.
The skin-brain-gut axis is becoming particularly important in diseases such as psoriasis and rosacea, as studies show an increased risk of heart attack and stroke in these patients. Chronic stress, which also affects the skin infection rate via the skin-brain connection, is increasingly recognised as a risk factor. These findings now enable dermatologists to develop targeted, improved diagnostic methods and therapies.
The link between skin diseases and cardiovascular risks is receiving increased attention. Dermatologists are now required to take these interactions into account in patient care. Prof. Gallo emphasises how important it is for patients with skin diseases to be screened for heart attack risks. In the near future, quantitative blood tests could help to identify high-risk patients more accurately.