Pfeiffer syndrome

Pfeiffer syndrome (ACS5) is characterized by craniosynostosis, malformed thumbs and toes, and partial syndactyly of the fingers and toes. The syndrome is underlined in three types depending on the severity.

Type 1 patients have only mild forms of brachycephaly, midface hypoplasia, and finger and toe abnormalities.

Type 2 is characterized by reticule skulls, severe forms of proptosis, finger and toe anomalies, ankylosis or synostosis of the elbow, and mental retardation.

Type 3 overflows with the symptoms of Type 2 but has no cloverleaf skull.

Pfeiffer syndrome (ACS5) is characterized by craniosynostosis, malformed thumbs and toes, and partial syndactyly of the fingers and toes. Depending on the condition, the syndrome is trimmed in three types.

Type 1 patients have only mild signs of brachycephaly, midface hypoplasia and finger and toe abnormalities.

Type 2 is characterized by Kleverlaehlel, severe manifestations of proptosis, finger and toe anomalies, ankylosis or synostosis of the elbow, and mental impairments.

Type 3 overflows with the symptoms of type 2 but has no cloverleaf skull