Spondylometaphyseal dysplasia

Spondylometaphyseal dysplasia is a disorder of the vertebral body development that manifests in the second year of life with walking and growth disorders. Flattened vertebrae and metaphyseal lesions on the hip and knee are characteristic of the disease.

Depending on the type, the severity differs according to severity and place of manifestation. The most common type is Kozlowski, which is characterized by severe kyphoscoliosis and is inherited as an autosomal dominant.