Tracheobronchopathia osteochondroplastica affects the large airways and is characterized by the development of multiple cartilaginous and cartilaginous nodules in the submucosa of the trachea and the main bronchi. As a result, the anatomy of the airways changes. The bronchial secretions can no longer be easily coughed off, which significantly narrows the airways.
Typically, the disease is very slow and usually remains unaltered over several years.
The cause of the disease is still unknown. Mostly it manifests in adulthood.