• The pyruvate kinase M2 as a regulator of autoimmune processes

    Today's article deals with a recently published Brazilian scientific study on an enzyme that can cause T-helper cells to go awry.

  • The MS Virtual Meeting 2020 (Part II)

    In this second article, you will find highlights on the role of microbiome and comorbidities in multiple sclerosis, presented at the joint ACTRIMS and ECTRIMS annual congress.

  • The MS Virtual Meeting 2020 (Part I)

    This article provides an overview of highlights and clinical studies on remyelination, EBV-specific immune therapies and the prodromal phase of MS from the joint ACTRIMS and ECTRIMS annual congress.

  • Type 2 diabetes remissions: a practical goal for primary care

    New evaluations of data from the DiRECT study show for the first time that, after weight reduction, not only diabetes remissions are possible, but also the pancreas morphology returns to normal.

  • Could near infrared light (NIR) be a new treatment for Parkinson's disease?

    Can light pulses also protect neurons of the substantia nigra from destruction? After promising observations from animal models, several human studies are in their early stages.

  • E-cigarettes: Does the heating element matter?

    A recent study warns of serious lung damage (EVALI) from e-cigarettes with heating elements made of nickel-chromium alloys. The life-threatening complications occurred without the use of nicotine or THC.

  • Noradrenalin may contribute significantly to sepsis-induced immune paralysis

    Norepinephrine leads to a dysregulation of immune response and a compromise of the defense function according to a study published in the American Journal of Respiratory and Critical Care Medicine.

  • Disease management as therapy target: how emotional acceptance contributes to better experiences and results

    Psychological stress in cancer diagnosis and therapies can influence immunity, with an effect on health and even on the course of disease.

  • Deafness infertility syndrome: Often overlooked in normozoospermia

    A young male patient presents an unfulfilled desire to have children but the spermiogram shows normozoospermia. The man also has poor hearing. Could genetics be relevant?

  • What is the diagnostic significance of vitreous Neurofilament Light Chains (NfLs)?

    The eye is a biological extension of the brain. Unsurprisingly various diseases such as glaucoma, cataract, or macular degeneration, may be associated with neurodegenerative disease.

  • Medical Case: One vacation ends in illness

    A report published in JAMA Neurology underlines the importance of physical examination and contextualization, especially for people returning from a trip.

  • Medullary fibroblasts of the thymus are decisive for central tolerance

    In immunology, fibroblasts play a decisive role in self-tolerance, not least because of their supply of different self-antigens. A research group from Tokyo has come to this conclusion.

  • It's time for a new understanding of Parkinson's disease

    Parkinson's disease, now the fastest-growing neurological disease in the world is still widely perceived as a disease of old, frail people. Current data demands an update to our understanding of it.

  • General practitioners should not attempt a mild COPD diagnose

    The frequency of false-positive COPD diagnosis is high. This could expose many patients in whom there is certainly no obstruction to the possible side effects of drugs.

  • The role of ketone bodies in glaucoma prevention

    A low-carb diet can have a preventive effect against some primary open-angle glaucomas. The preventive neuroprotective effect of such diets is known against Alzheimer's disease, epilepsy, and Parkinson's disease.

  • Stop smoking. If not now, when?

    Nicotine patches as protection against COVID-19? This daring hypothesis has been proposed in France. In South Africa, however, smoking is now completely banned.

  • Ten data protection errors we can avoid in our daily medical routines

    Highly sensitive data are processed in our medical settings. Human errors may lead to data mishaps, due to limited knowledge of privacy protocols. Common errors that can be easily avoided are listed.

  • Immune checkpoint inhibitors (ICIs) may be associated with gonadotoxicity

    A small but exciting new study is the first to describe gonadotoxicity of immune checkpoint inhibitors (ICIs) based on autopsy findings. Association of ICIs with impaired spermatogenesis is suspected.

  • PIMS-TS: A new disease raises many questions

    The SARS-CoV-2 has been suspected to cause severe inflammatory disease in children. The results of an English case-control study suggest a new type of inflammatory syndrome after COVID-19 infection that differs from the Kawasaki syndrome known to the medical community.

  • Preventing dementia by preventing strokes

    Apoplexy and dementia present risk factors in common, most of which can be managed. It is estimated that about 35% of dementia cases could be prevented by stroke prevention.

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