• Reflux in infants does not usually require treatment

    Gastro-oesophageal reflux and regurgitation often cause parental concern, but only few babies have a pathology that requires treatment.

  • Glomerulonephritis: vitamin B2 derivatives alleviate disease course

    Most of these kidney inflammations show a chronic progressive course and can result in terminal renal insufficiency. But scientists improved renal chronic inflammatory processes.

  • Prediabetes: Impaired fasting glucose increases the risk of gastrointestinal carcinomas

    It doesn't have to be manifest diabetes. Even slightly elevated glucose levels over several years are enough to increase the risk of gastrointestinal cancer. This is the result of a population study from South Korea.

  • Severe VWD: prophylaxis reduces bleeding

    The clinical evidence in favour of prophylaxis for von Willebrand disease has so far been sparse. This is changing with the data from the WIL-31 study.

  • Also check the liver in dementia cases

    A recent study argues for a treatable cause behind dementia symptoms: hepatic encephalopathy, in the context of unrecognised liver cirrhosis.

  • A vaccine against pancreatic and colon cancer?

    A vaccine has shown to prevent the recurrence of pancreatic and colon cancer with KRAS mutations in patients who have previously undergone surgery.

  • Palliative care guidelines for advanced lung diseases

    The ERS working group recommends integrating palliative care and advance directives into routine COPD and ILD care at an earlier stage, so patients and relatives feel comfortable and supported.

  • Localised prostate carcinoma: active monitoring is no worse than surgery or radiotherapy

    In the case of early prostate cancer, active surveillance prevents just as many deaths as surgery or radiotherapy. This is confirmed by 15-year data from the large randomised 'ProtecT' study.

  • How to predict the severity of gestational diabetes

    The CHANGED Score promises an early identification insulin dependence risk in gestational diabetes. Future studies should ensure its validity in different contexts.

  • Polypharmacy (Part II): overmedication and mismedication are common in dementia patients

    Older dementia patients have more polymedication compared to dementia-free elderly patients. Included medications may lead to more serious side effects in this group.

  • Polypharmacy (Part I): a bigger problem than we think?

    Polypharmacy is often associated with negative outcomes. According to a recent study, hospitalisation rates due to side effects have more than doubled.

  • Early detection of Parkinson's disease using OCT diagnostics

    Parkinson's disease may begin as early as 20 years before typical symptoms manifest. Will optical coherence tomography become a key predictive tool?

  • Mindfulness training improves quality of life in neurofibromatosis

    The randomised controlled trial results support a mindfulness program tailored to patients with neurofibromatosis in routine care.

  • Can Alzheimer's be detected in the gut microbiome before cognitive impairment appears?

    An altered gut microbiome may precede the clinical signs of Alzheimer's disease. Can the gut microbiome be used as an early biomarker?

  • Vaping: also harmful if cannabidiol replaces nicotine

    Many erroneously assume that e-cigarettes are not as harmful as normal cigarettes. Unfortunately, this is not the case, according to a recent study.

  • Artificial intelligence and skin cancer

    AI is already used in medical diagnostics. Could the diagnosis and therapy of pigmented skin lesions benefit from it in a realistic clinical scenario?

  • How metastases invade the body

    New research shows how cancer cells invade healthy tissue, offering new clinical targets against metastasis and potentially changing how cancer is treated.

  • Statin therapy for liver protection?

    More people are developing liver damage or liver carcinoma. Can the rising number of deaths caused by these be reduced? Statins may be an option.

  • Eosinophilic oesophagitis: the milk does the trick

    Eliminating certain foods can help cure eosinophilic oesophagitis. But it is often unclear which to eliminate or abstain from. Researchers compared elimination diets of different foods, versus those where only cow's milk was avoided.

  • Maternal infections increase the risk of leukaemia

    Maternal infections during pregnancy are suspected of increasing leukaemia risk in children. A new study investigated this claimed correlation.

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