• A vaccine against pancreatic and colon cancer?

    A vaccine has shown to prevent the recurrence of pancreatic and colon cancer with KRAS mutations in patients who have previously undergone surgery.

  • Palliative care guidelines for advanced lung diseases

    The ERS working group recommends integrating palliative care and advance directives into routine COPD and ILD care at an earlier stage, so patients and relatives feel comfortable and supported.

  • Localised prostate carcinoma: active monitoring is no worse than surgery or radiotherapy

    In the case of early prostate cancer, active surveillance prevents just as many deaths as surgery or radiotherapy. This is confirmed by 15-year data from the large randomised 'ProtecT' study.

  • How to predict the severity of gestational diabetes

    The CHANGED Score promises an early identification insulin dependence risk in gestational diabetes. Future studies should ensure its validity in different contexts.

  • Polypharmacy (Part II): overmedication and mismedication are common in dementia patients

    Older dementia patients have more polymedication compared to dementia-free elderly patients. Included medications may lead to more serious side effects in this group.

  • Polypharmacy (Part I): a bigger problem than we think?

    Polypharmacy is often associated with negative outcomes. According to a recent study, hospitalisation rates due to side effects have more than doubled.

  • Early detection of Parkinson's disease using OCT diagnostics

    Parkinson's disease may begin as early as 20 years before typical symptoms manifest. Will optical coherence tomography become a key predictive tool?

  • Mindfulness training improves quality of life in neurofibromatosis

    The randomised controlled trial results support a mindfulness program tailored to patients with neurofibromatosis in routine care.

  • Can Alzheimer's be detected in the gut microbiome before cognitive impairment appears?

    An altered gut microbiome may precede the clinical signs of Alzheimer's disease. Can the gut microbiome be used as an early biomarker?

  • Vaping: also harmful if cannabidiol replaces nicotine

    Many erroneously assume that e-cigarettes are not as harmful as normal cigarettes. Unfortunately, this is not the case, according to a recent study.

  • Artificial intelligence and skin cancer

    AI is already used in medical diagnostics. Could the diagnosis and therapy of pigmented skin lesions benefit from it in a realistic clinical scenario?

  • How metastases invade the body

    New research shows how cancer cells invade healthy tissue, offering new clinical targets against metastasis and potentially changing how cancer is treated.

  • Statin therapy for liver protection?

    More people are developing liver damage or liver carcinoma. Can the rising number of deaths caused by these be reduced? Statins may be an option.

  • Eosinophilic oesophagitis: the milk does the trick

    Eliminating certain foods can help cure eosinophilic oesophagitis. But it is often unclear which to eliminate or abstain from. Researchers compared elimination diets of different foods, versus those where only cow's milk was avoided.

  • Maternal infections increase the risk of leukaemia

    Maternal infections during pregnancy are suspected of increasing leukaemia risk in children. A new study investigated this claimed correlation.

  • Sleep disorders and rheumatic diseases reinforce each other

    In people with rheumatic diseases, lack of sleep can increase systemic inflammation and pain sensitivity and exacerbate the consequences of an already overactive immune system.

  • Morning stiffness: don't just think of arthritis

    Doctors often initially think of inflammatory arthritis when it comes to prolonged morning stiffness in the joints. However, a recent study shows that the symptoms can also occur with osteoarthritis.

  • Gene changes caused by plastics during in vitro fertilisation

    Researchers found that placental gene expression is significantly altered in mice after IVF. Could it be due to the plastics used in the procedure?

  • Polypectomy: repeated colonoscopies are not necessary

    For a successful polypectomy, a good colonoscopy is the key. The procedure should only require one colonoscopy, but many undergo several. Improvement is much needed.

  • Hormone replacement therapy is associated with increased dementia risk

    A large Danish registry study reported a 24% increased risk of dementia after oestrogen-progestin therapy.

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