• New classification of prediabetes

    Not everyone with high blood glucose or HbA1C levels will go on to develop type 2 diabetes. With a new classification in six clusters, an attempt is now being made to better assess the individual risk.

  • Rheumatic diseases: the right practice management up to the Corona vaccination

    Continue or pause immunosuppressive therapy - a decision that currently confronts rheumatologists with a major challenge. A recent study examines the influence of COVID-19 on the immune system.

  • Blood pressure difference provides information on mortality risk

    Blood pressure is rarely measured in both arms. A new study shows that even a small difference in systolic blood pressure of 5 mmHg between arms significantly increases cardiovascular risks and all-cause mortality.

  • Loneliness in developmental years damages neuronal networks important for social behaviour

    Studies describe that social isolation in childhood and adolescence has negative effects on brain function and sociability in adulthood, but the mechanisms were poorly understood until now.

  • Diabetes as a risk factor for COVID-19

    We look at a review suggesting possible biological mechanisms that could make SARS-CoV-2 infections particularly dangerous for patients with diabetes.

  • Rheumatoid arthritis increases cardiovascular risk

    Patients with coronary heart disease have a higher risk of cardiovascular events if they also have rheumatoid arthritis, according to a major Danish study published in May 2020.

  • Treat-to-target: A promise in axial spondyloarthritis

    Patients with axial spondyloarthritis could benefit from a treat-to-target concept similarly applied in rheumatoid arthritis patients. This approach is supported by the TICOSPA study.

  • Metformin and COVID-19

    Type 2 diabetes is considered an important risk factor for a severe course of COVID-19. It is unclear what role antidiabetic drugs play in this process. Metformin, for example, could have a more beneficial effect.

  • Computer detects diastolic dysfunction in ECG

    A new computer program is now able to predict the rapid relaxation of the left ventricle - a measure of diastolic function - with a high degree of accuracy using a simple ECG.

  • Giant cell arteritis: Will sonography replace biopsy soon?

    Ultrasound is gaining importance as a diagnostic method for rheumatic diseases. It can show intima media thickenings in detail and diagnose vasculitis with high sensitivity.

  • Familial risk of prostate cancer and in situ neoplasia

    A new study has shown that the risk of prostate cancer is similarly increased in families with a high incidence of precancerous lesions. This could therefore be relevant for individual early detection and counseling.

  • Healing after spinal cord injury - is the potential of resident stem cells more tangible than we thought?

    A study raises hope: by switching on a single factor in the body's own stem cells of the epenzyme, it was possible to generate considerable new oligodendrocyte formation after injury.

  • Germany and COVID-19: More diabetes cases in children?

    Mental stress and viral infections are considered risk factors for the development of type 1 diabetes in children. Should we expect an increase in incidence amidst the lockdown?

  • Oxytocin reverses amyloid-related cognitive impairment

    A new groundbreaking study focusing on the "cuddle hormone" provides another biochemical explanation of why people with dementia need a lot of personal closeness and care.

  • Prostate cancer: A diversity of treatments exist today

    Treatment options now range from active monitoring, radiotherapy with or without adjuvant endocrine therapy, prostatectomy, or palliative care. What do patients pay particular attention to?

  • Tofu protects against coronary heart disease

    According to a new study, the consumption of tofu reduces the risk of developing coronary heart disease. The isoflavones contained in tofu seem to mediate part of the protective effect.

  • Infection and cancer: A global “inventory-check”

    Infectious pathogens represent a very widespread, modifiable risk factor in oncology. To date, however, there have been no reliable surveys on the actual worldwide prevalence of infection-related cancers.

  • Zoster risk is highest among JAK inhibitors

    Therapy with DMARDs increases the already higher risk of herpes zoster (shingles) in patients with rheumatoid arthritis. The risk is highest for JAK inhibitors as shown by the RABBIT registry.

  • New human studies on gene therapies for amyotrophic lateral sclerosis (ALS)

    Two recent studies have shown that personalized therapy for neurodegenerative diseases associated with single-gene mutations could be within reach.

  • Cancer patients often suffer already from comorbidities

    The risks posed by multimorbidity and polymedication increase from initial diagnosis, especially in elderly cancer patients. A Danish research team has investigated this combination for 20 types of cancer.

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