• Iran: Calls to save a doctor sentenced to death

    Dr Hamid Ghareh-Hassanlou and his wife Farzaneh were convicted after a trial on 30 November. The radiologist is now facing execution. International doctors and medical associations are now mobilising to prevent the execution.

  • Deuruxolitinib, a novel JAK inhibitor, proves effective in alopecia areata

    The inhibitor was highly effective in severe alopecia areata with a high % of satisfied or very satisfied patients.

  • A new biologic treatment for HS: secukinumab is on the doorstep

    Secukinumab achieved a clinical response in over 40% of hidradenitis suppurative patients and reduced abscesses and pain, and improved quality-of-life.

  • Preventing stress eating, and achieving weight targets

    Chronic stress releases cortisol. Studies show that this increases cravings for high-calorie, sweet, fatty and processed foods. A challenge for many overweight people.

  • PsoBest registry reveals: Genital psoriasis is often followed by sexual dysfunction

    An analysis of 811 surveys shows nearly half of psoriasis patients have psoriatic lesions around the genital region and other areas of sexual interest.

  • Medical emergencies: when music helps (Part 1/3)

    Are you a rock fan? According to a study, if "Highway to Hell" riffs at high volume in the operating theatre, there's a good prognosis!

  • Nalbuphine: another candidate for an approved treatment in prurigo nodularis?

    Significantly more patients on nalbuphine achieved at least a 4-point decrease on the worst itch (WI-) numeric rating scale (NRS), QoL rose, and skin lesions improved.

  • Sotorasib shows superior PFS and ORR over docetaxel in previously treated NSCLC

    Improvement seen in progression-free survival and ORR by the selective KRAS G12C inhibitor over docetaxel in previously treated KRAS G12C-mutated NSCLC.

  • Kappa-opioid receptor agonist shows remarkable efficacy in notalgia paresthetica

    Difelikefalin leads to rapid decrease in pruritus in notalgia paresthetica, a very common, underdiagnosed condition with a lack of treatment possibilities.

  • Selective IL-23 inhibitor shows long-term efficacy in active PsA

    KEEPsAKE 1 and 2 trials demonstrated high efficacy of the IL-23 blocker risankizumab in adult patients with active psoriatic arthritis independent of previous therapy.

  • Fern extract reverses UV induced cell damage and occurrence of new lesions

    A local and oral preparation of polypodium leucotomos extract led to clinical reversal of actinic keratosis lesions at 12 months.

  • When lightning strikes: tips for emergency management

    Dr. Robert McMickle, an emergency physician at Harbor UCLA Medical Center in Los Angeles, delves into the topic of lightning injuries.

  • Colonoscopy as a screening examination

    A trial on colonoscopy for colorectal cancer prevention showed that a physician invitation for a screening check-up reduced incidence but not mortality.

  • Roflumilast 0.3% foam beneficial in various aspects of seborrheic dermatitis

    A new study shows over 80% of primary endpoint reach of clear or almost clear skin, according to the Investigator's Global Assessment at week 8.

  • Activation of the A3 adenosine receptor: a new mode of action to treat psoriasis?

    Piclidenoson reached its primary endpoint with a statistical difference over placebo while showing a very good safety profile but did not outperform apremilast.

  • Deucravacitinib demonstrates stable, long-term maintenance

    Deucravacitinib performed with durable efficacy. Up to week 112, results in various outcome measures were consistent with those at week 52.

  • Biologic therapy in HS patients: unmet needs due to high rate of non-responders

    Biologics were recently approved for hidradenitis suppurativa, but many patients who do not respond efficiently experience a significant disease burden.

  • Heart palpitations after partying? This is a serious matter

    Excessive salt and alcohol consumption can trigger unpleasant events. One of these is the little-noticed Holiday Heart Syndrome.

  • Assoc Prof. Vaghefi: AI helps predict cardiovascular risks in retina scan

    Associate Prof. Vaghefi discusses AI retina scan algorithms, how the retina can detect other health issues, and how the retinal tech was deployed in rural India.

  • JAK3/TEC blockade leads to long-term improvement in alopecia areata

    Ritlecitinib sustained efficacy in treatment up to month 36 without new safety signals. Patient-reported outcomes improved already after 3 months.

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