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Prof. Axel Merseburger reviewed the recent evidence testing immuno-oncology (IO) in combination with tyrosine kinase inhibitors (TKIs) in metastatic renal cell carcinoma (mRCC).
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Pharmacologists have succeeded in detecting minute amounts of the coronavirus SARS-CoV-2 using mass spectrometry in solutions with which COVID-19 patients gargled. The new method could serve as a supplement to previously used tests.
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Adding docetaxel to antiandrogen treatment improves progression-free survival (PFS) in prostate cancer patients with prostate-specific antigen (PSA) relapse.
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Aquablation demonstrated a significantly lower rate of sexual dysfunction at the primary safety endpoint of 3 months compared with transurethral resection of the prostate (TURP), according to phase-3 data.
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In his state-of-the-art lecture, Prof. Leendert Looijenga discussed the connection between infertility and testicular cancer1. Both molecular associations and putative causality were reviewed.
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New findings from the large, multicentre IRON study demonstrate that robot-assisted partial nephrectomy (RAPN) is associated with lower morbidity and similar oncologic and long-term renal function outcomes compared with open partial nephrectomy (OPN).
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Labeled prostate-specific membrane antigen in PET-CT fusion was superior in specificity and sensitivity to conventional imaging in pre-treatment staging of intermediate and high-risk localized prostate cancer.
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The neurological history from male LUTS patients or their partners is essential. Urologists should perform a careful physical exam and perhaps a referral to neurologists prior to any invasive or irreversible treatment.
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A highly contagious disease breaks out in Italy and threatens to contaminate the whole of Europe. Sick people remain in isolation. Caregivers risk their lives to protect them in a world in crisis. This disease had nothing to do with the medical field.
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The trial demonstrated a significant survival advantage for intermediate and poor-risk patients with metastatic renal-cell carcinoma who received pembrolizumab + axitinib as compared to those receiving sunitinib.
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Prof. Yohann Loriot discussed novel treatment options beyond immunotherapy, urging a better understanding of tumor biology towards identifying new targets and facilitating precision medicine.
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A study investigating nadofaragene firadenovec for high-grade, BCG-unresponsive non-muscle invasive bladder cancer (NMIBC) achieved encouraging, durable, high-grade, recurrence-free survival.
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Reduction in the frequency of BCG vaccine instillations during induction and maintenance treatment for non-muscle-invasive bladder cancer results in earlier disease recurrence relative to a standard schedule.
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New findings from the first prospective, multicenter, randomized trial demonstrated improved continence for patients undergoing robotic-assisted radical prostatectomy as compared with conventional laparoscopic radical prostatectomy.
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Prof. Dr. De Win is an expert in Adolescent, Paediatric and Reconstructive Urology at the Department of Urology, Universitair Ziekenhuis, Antwerp, Belgium.
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Several clinical studies have reported persistent neurological and cognitive damage even after remission, whose incidence, duration, and the underlying mechanism are not yet known. The role of mechanical ventilation and hippocampal damage has been suggested.
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Billions of genes can be examined simultaneously with "Next Generation Sequencing". The method helped researchers identify a gene mutation causing a rare hormone disease. Such precision medicine could develop tailor-made therapies and avoid side effects.
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Women who had cancer in childhood have a higher risk of developing heart and circulation problems. Dr. Marina Panova-Noeva, a scientist at the German Centre for Cardiovascular Research (DZHK) is investigating the molecular mechanisms responsible for this.
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French company Diabeloop SA now operates on the German market as Diabeloop GmbH as it expands its international operations. They aim to offer innovative technologies for the management of type-1 diabetes.
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A 16-year-old boy is examined in the ER because of chest pains. Careful investigation by physicians reveals acute myocarditis and SARS-CoV-2 infection. The young patient, apart from fever, never showed any typical signs of COVID-19.
