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The results of an 18-year long-term study showed that ozone pollution significantly contributes to the accelerated development of pulmonary emphysema.
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A lizard-like animal that lived in the Permian 289 million years ago suffered from a disease of bone metabolism similar to the Paget's disease in modern humans. This is by far the oldest known evidence of such a disease and the oldest indirect evidence of a viral infection.
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Scientists from the Berlin Institute of Health and the Charité University Hospital in Berlin have specifically changed the control ranges of 20 disease-relevant genes. This enabled them to identify those changes that have the greatest influence on disease processes.
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HIV-positive cancer patients have a worse outcome with prostate cancer and breast cancer. Carcinomas progress more rapidly and cancer-related mortality also increases.
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Motor learning takes place both during the active practice of new processes and in the breaks afterward. New research shows that the consolidation of practiced sequences already begins during short interruptions of practice and can be improved by brain stimulation.
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Surgical wounds close more frequently and faster, infections are rarer than with standard care. However, 23% of the data from completed studies are still not available.
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External measurements taken on the scalp allow conclusions to be drawn about the underlying nerve cell activity.
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Researchers at John Hopkins University have identified a pair of proteins that control when hair cells form in mammalian ears, to great precision. The research team believes these proteins may help restore hearing in people with irreversible deafness.
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New SLE classification criteria intend to help patients with SLE to be recognized more quickly and to be treated more effectively.
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Tattoos could become interesting from a diagnostic point of view. Scientists have succeeded for the first time in developing tattoos that work like disease-indicating sensors.
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Timely lifestyle changes can protect people at high risk of age-related macular degeneration (AMD) from vision loss into old age. This is a key intermediate result of the European research project EYE-RISK.
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Dr. Philipp Kellmeyer, a researcher at the Freiburg University Hospital (Germany), calls for more sensitive use of virtual realities in medicine and nursing.
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Overactive nerve cells in certain areas of the brain are considered an early symptom of Alzheimer's disease. For the first time, a team from the Munich Technical University (TUM) was able to elucidate the causes and mechanisms of this initial and important step.
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Severe and persistent pancreatic pain is difficult to treat because many painkillers do not work in this organ. In a recent study, a team has discovered the reason: A certain endogenous nerve messenger substance is present in the pancreas’ nerves in very high concentrations.
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Researchers found that in people with celiac disease, following gluten ingestion, certain inflammatory molecules associated with clinical symptoms occur in the bloodstream. These recently discovered biomarkers are the basis for the blood test.
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Therapy with the PARP inhibitor olaparib prolonged progression-free survival in severely pretreated patients with metastatic castration-resistant prostate cancer and defective DNA repair mechanisms by approximately 4 months compared to hormone therapy with enzalutamide or abiraterone.
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Food allergies can be caused by the absence of certain intestinal bacteria. Current study results show that the replacement of these intestinal bacteria could make a decisive contribution to the treatment of allergies.
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The PD-L1 inhibitor atezolizumab, when added to chemotherapy, prolonged the progression-free survival of untreated patients with metastatic bladder cancer from 6.3 to 8.2 months compared to chemotherapy.
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Additional treatment with abemaciclib or ribociclib may prolong survival in women with advanced hormone receptor-positive and HER-2-negative breast cancer.
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Tumors with mismatch repair deficiency (MMRD) or tumors with high tumor mutational burden (TMB) respond better to therapy with checkpoint inhibitors than tumors without these properties.
