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A new study reconstructed a COVID-19 transmission process in a restaurant in Guangzhou, China. It may have been a restaurant's air conditioning system that allegedly spread CoV-2 SARS to nine people sitting next to an infected person.
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According to the results of a preprint study, 4.6% of blood donors in the Milan metropolitan area already had antibodies against the coronavirus at the beginning of the epidemic. This number rose to 7.1% by the beginning of April.
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The WHO warns against the issuing of "immunity passports" that would allow people with SARS-CoV-2 antibodies to resume their activities or to travel. To date, there is no evidence that these people are immune to reinfection. The reliability of the tests is also in question.
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A freely-downloadable document is born from the confluence of scientific literature, social issues, physicians’ experiences in clinical practice, and exchange amongst colleagues.
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A study group compared the SARS virus and the new coronavirus responsible for COVID-19. Some differences are highlighted in the interaction of viruses with the ACE2 receptor and the enzyme TMPRSS2.
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Dr. Isabel Muñoz was a family physician in Salamanca, Spain. Her passing at 59 years old, brings into question the protection of health professionals and of people in quarantine.
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Michael J. Peluso, University of California, San Francisco (USA), presented at the virtual CROI in March 2020 the largest case series to date of patients who developed early HIV infection under PrEP.
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Thanks to modern antiretroviral therapy, the life expectancy average of HIV-infected people has improved significantly. It is now only 3.3 years less than that of non-infected persons. However, many of them suffer from comorbidities.
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HIV-infected people often suffer from sleep disorders, which in turn increases the risk of a heart attack. An analysis of CNICS patient groups showed that patients with stressful insomnia increase the risk of type 2 myocardial infarction.
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In the ADVANCE study, treatment with dolutegravir+tenofovir alafenamide+emtricitabine was associated with a higher risk of obesity, metabolic syndrome, increase in visceral and subcutaneous fat, and long-term risk of developing diabetes.
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Metabolic complications are a major challenge of HIV infection and antiretroviral therapy (ART). Many of these complications are mediated by adipose tissue. Current knowledge on this topic was presented at the virtual CROI 2020.
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Long-acting antiretroviral therapeutics might be particularly suitable for patients who have problems swallowing, who fear stigmatization or who do not want to take medication every day.
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ROADMAP study showed that a kick-and-kill strategy with the HDAC inhibitor romidepsin and the bNAb 3BNC117 proved to be ineffective in 20 patients with chronic HIV infection under long-term ART.
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The effect of intramuscular administration of long-acting cabotegravir and rilpivirine is not inferior to monthly injections in maintenance therapy for patients with HIV infection, as found by the ATLAS-2M study.
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The Italian Society of Anesthesia, Analgesia, Resuscitation and Intensive Care (SIAARTI) has just published its clinical ethical guidelines for exceptional conditions, in the context of the Covid-19 epidemic.
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Men who have sex with men (MSM) are disproportionately affected by STIs, and HIV pre-exposure prophylaxis may play a role in their rise. Increasingly, STIs in MSM may be extragenital and asymptomatic.
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Antiretroviral therapies (ART) are enabling HIV+ people to have an almost unaffected life expectancy and the need for elderly care. Elderly HIV+ patients suffer from particular comorbidities that need to be addressed.
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Dr. Omar Alquati is a physician working at the Lodi Local Health Authority in Italy. He works in intensive care units but is currently a COVID-19 patient at Pavia's San Matteo Polyclinic. He shared his thoughts and experience since becoming infected.
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Tumor diseases and intensive chemotherapy deplete the body's iron reserves. Iron deficiency and anemia can impair prognoses. A rapid diagnosis and iron deficiency therapy is therefore indicated.
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Cancer prevalence will continue to rise worldwide in the future. However, more and more people are surviving their tumor disease. Nevertheless, many people may struggle for life with the after-effects.
