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An international research group led by Victoria Pascal from the Department of Gastroenterology, Vall d'Hebron Research Institute in Barcelona, has succeeded in identifying patients with Crohn's disease (CD) solely from stool samples.
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The Von Willebrand Factor (VWF) is a carrier protein of blood coagulation factor VIII and captures platelets at locations with vascular damage. It undergoes conformational changes within the A1 domain and through the development of the A2 domain. Its size and function are regulated by the metalloproteinase ADAMTS13. ADAMTS13 deficiency can, therefore, lead to the life-threatening disease thrombotic thrombocytopenic purpura (TTP).
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Every day, stem cells in our bone marrow produce billions of new red blood cells. Any disruption in this process can result in serious disease. Researchers have succeeded in furthering our understanding of how blood cells are formed.
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Rivaroxaban could be a therapy option, especially if it is administered early, explained Prof. Dr. Jan Beyer-Westendorf in a session at the GTH in Vienna. The physician presented a small series of cases from the prospective non-interventional multicentre Dresden NOAC registry.
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Since 1980, several scientific advances have been made in the treatment and prevention of colon cancer. Recent discoveries linking it to a possible bacterial genesis would make it viable to design new methods for improving its detection and prevention.
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The sterile alpha motif (SAM) and histidine-aspartate domain-containing protein 1 (SAMHD1) is a triphosphohydrolase that catalyzes the hydrolysis of deoxyribonucleoside triphosphate into deoxyribonucleoside and triphosphate. Ian A. Taylor, from the Francis Crick Institute in London, reported on new insights about the structure and mechanism of the enzyme at the 25th CROI in Boston on March 6, 2018
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The enormous potential of RNA-based therapies was presented by Prof. Dr. med. Stefanie Dimmeler from the Institute of Cardiovascular Regeneration in Frankfurt am Main during the 62nd Annual GTH Meeting in Vienna.
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Along with the improvement in life expectancy in our society, we are witnessing an increase in the dependence of the elderly. Improving the number of years lived in good health is the current challenge to overcome in order to limit the avoidable loss of autonomy and improve the quality of life of seniors.
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Neutralizing antibodies could be suitable for early treatments and to maintain small reservoirs of defense cells’ retrovirus genes. Malcolm Martin from the National Institutes of Health presented current animal experiments looking into this therapeutic approach at the 25th CROI on March 5th, 2018, in Boston.
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Playing violent action adventure games for prolonged periods does not make adults more aggressive say researchers from the Max Planck Institute for Human Development and the University Clinic Hamburg-Eppendorf in Germany.
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Can acupressure achieve a sustained reduction in menstrual pain? Is an app-based self-care program particularly attractive to young women? These questions were addressed in a new study by researchers from Charité – Universitätsmedizin Berlin.
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Brown adipose tissue has played a key role in prevention research since its presence was first documented in adults. However, there was no non-invasive method of measuring its heat generation.
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The 25th CROI in Boston provided an opportunity for Harold W. Jaffe from the Atlanta-based Centers for Disease Control and Prevention (CDC) to look back into the development and evolution of AIDS research, and lessons learned since the start of the epidemic in the first plenary session.
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It's no new news that viruses cause cancer. For example, human papillomavirus (HPV) causes almost all of the more than 500,000 annual worldwide cases of cervical cancer. By driving the proliferation of infected cells, viruses speed manufacture of more viruses, but excessive cellular proliferation is also a hallmark of cancer.
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Once a campaign promise of incumbent French President Emmanuel Macron, the “Health Service” will be a requisite for France’s 47,000 medical students and is set to start in September 2018.
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At the end of January, Apple announced the integration of a new function which will allow users to access their health records from multiple providers within the existing Health app.
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Every person with hemophilia is different and this demands tailor-made treatments, both in the preparations of dosage factors to be substituted and in the treatment prevention of disease-related changes in joints.
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The European Medicines Agency (EMA) has begun a reevaluation of the risk/benefit ratio for ESMYA (Ulipristal acetate), a drug for treatment of uterine fibroids in women of childbearing age. This decision follows five cases of severe hepatic insufficiency in Europe.
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What effect does a particular cancer medicine or radiation therapy have on patients? To find out, physicians use CT images to determine whether a tumor’s size changes during the course of treatment.
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Scientists have identified a single genetic change in Salmonella that is playing a key role in the devastating epidemic of bloodstream infections currently killing around 400,000 people each year in sub-Saharan Africa.
