• Dr Pedro Mendes Bastos on AD differences between children and adults

    Dr Mendes Bastos addressed the heterogeneity of atopic dermatitis patients, causes, and therapy options, and the ongoing research to address them.

  • Promising results in AD treatment with an OX40 ligand inhibitor

    Clinically meaningful improvements in Eczema Area and Severity Index (EASI) were observed with amlitelimab treatment for atopic dermatitis.

  • Skin tape stripping: Can it pave the way for early diagnosis in HS?

    Skin tape stripping is an effective, non-invasive way to detect biomarkers associated with early disease in hidradenitis suppurativa.

  • Alopecia areata: Ritlecitinib generates substantial re-growth of scalp hair

    Excluding severe AA, 83–93% of participants in the ALLEGRO-LT trial reached an 80% re-growth of scalp hair or more after 15 months of treatment.

  • IL-23p19 inhibitors have a superior drug survival compared with other biologics

    A cohort study from the BADBIR registry revealed that IL-23p19 inhibitors are associated with the highest drug survival regarding effectiveness and safety.

  • Vitiligo: Oral JAK1 inhibitor induces increasing repigmentation over time

    Continuing povorcitinib treatment after a 6-month double-blind phase led to additional repigmentation for many participants of a vitiligo phase 2b trial.

  • Dupilumab: a future option for severe hand eczema?

    In a small study, treating different severe hand eczemas with dupilumab led to favourable results. At week 16, 19 of 20 participants reached HECSI75.

  • Patience is rewarded in initial non-responders to topical ruxolitinib with vitiligo

    Extended treatment with ruxolitinib cream resulted in substantial response rates in patients who had demonstrated no or little response after 6 months.

  • Women with psoriasis face increased adverse effects with systemic therapy

    Long-term conventional systemic therapies lead to higher drug-related adverse events and treatment discontinuation rates compared with biologics.

  • Nanobody sonelokimab shows efficacy in hidradenitis suppurativa

    The agent led to remarkable clinical responses for hidradenitis suppurative in the phase 2 MIRA trial. It was relatively well tolerated without new safety signals.

  • JAK inhibitor provides sustained skin clearance in adolescents and adults with AD

    Upadacitinib therapy led to robust clinical efficacy and itch relief in adolescents and adults with moderate-to-severe atopic dermatitis in 3 ongoing phase 3 trials.

  • Nemolizumab shows high success rates in prurigo nodularis

    Nemolizumab achieved the 2 primary endpoints in the phase 3 OLYMPIA 1 study for itch and Investigator’s Global Assessment success in prurigo nodularis.

  • Anti-IL17 blockade leads to maintained pain reduction in patients with HS

    A pooled analysis found that secukinumab treatment entailed a numerically greater pain reduction than placebo in patients with hidradenitis suppurativa.

  • Botanical drug solution improves AA hair regrowth for children and adolescents

    Twice-daily treatment with a plant extracts solution led to sustained hair regrowth in children and adolescents with alopecia areata in the phase 2/3 RAAINBOW trial.

  • Topical tapinarof: a rising star in atopic dermatitis

    Phase 3 results show its potential as a new agent for atopic dermatitis from early age. Over 45% of participants met the primary endpoint of clear or almost clear skin.

  • Update AMD: First drug approved for the treatment of geographic atrophy

    Over 5 million people globally suffer geographic atrophy linked to age-related macular degeneration. A new intravitreal drug was approved for its treatment.

  • Under the skin: tattoos and their consequences

    Tattoos are becoming increasingly popular, but these permanent body ornaments can cause considerable damage to the skin.

  • Proton-pump inhibitors and cancer therapy: a bad combination?

    Some retrospective studies suggested that combination of PPIs with immuno-chemotherapies, is associated with worse outcomes. What's new on this issue?

  • Medical Case: A patient with upper abdominal pain, nausea and fainting

    A 47-year-old female patient complains of an episode of fainting and unwanted weight loss, in addition to gastrointestinal issues. Could you guess a diagnosis?

  • When painful muscle cramps occur during sport: how to treat them?

    Athletes often treat cramps themselves, but the effectiveness of untargeted therapy is questionable. What helps with painful attacks and what doesn't?

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