• Developments in heart medicine affect millions of people

    From 25 to 29 August 2018, 31,000 participants from 150 countries are expected at the European Cardiology Congress in Munich, making the Congress of the European Society of Cardiology (ESC) one of the world's largest medical congresses.

  • Immuno-oncology: universally applicable or age-dependent?

    Immuno-oncology has been groundbreaking and provided patients with more valuable months of life. However, response rates still remain low at around 25%, and immunotherapy success in relation to age needs further research.

  • Rising temperatures and suicide

    New levels of heat may cause between 9,000 to 40,000 more suicides in the US and Mexico

  • Pneumonia in the emergency room: making smarter decisions

    Emergency rooms may be often overwhelmed, and in the heat of the moment, it is important to keep a cool head and yet be open to new recommendations that can help us make wise decisions.

  • WhatsAppitis: watch out for smartphone abuse

    Some medical experts are seeing a rise in cases. In this uncommon phenomenon, thumbs and wrists are overstretched for writing messages, causing sharp pain.

  • Artificial meat is coming soon

    Mosa Meat, a Dutch-based start-up, is creating the first non-animal meat, fully produced in a laboratory.

  • Vitamin D deficiency could be a risk factor for Interstitial Lung Disease (ILD)

    A 10-year long observational study finds a link between low levels of Vitamin D and an increased incidence of inflammatory diseases of the lung including ILD

  • The lower, the better? - Extremely low LDL values in CHD prevention

    With the availability of the new PCSK9 inhibitors Alirocumab and Evolocumab, LDL values can be reduced to below 20 mg/dl for the first time. What is the advantage of such low values? Are patients at risk? A new study provides information.

  • What are human papilloma viruses, and are all HPV types dangerous?

    Human papillomaviruses play an important role in the development of genital warts and the far more dangerous cervical carcinoma. There are well over 140 different HPV types, of which around 40 can infect the anogenital region.

  • New findings on the clinical benefit ustekinumab for patients with SLE

    Safety was as expected based on earlier experience with the agent in psoriasis, psoriatic arthritis (PsA), and Crohn’s disease (CD). Based on these results, ustekinumab may have the potential to offer a new treatment option for patients with SLE.

  • The importance of vitamin A for the intestinal immune system

    The intestinal immune system must constantly maintain the difficult balance between fighting infections and simultaneously tolerating harmless or useful germs, and our food components.

  • Long-term safety profile of adalimumab across indications confirmed

    A recent data analysis of 78 clinical trials of adalimumab demonstrated an overall safety profile consistent with previous findings and the tumor necrosis factor (TNF) inhibitor class.

  • Counteracting insulin resistance with metformin

    There are many type 1 diabetes patients who, despite insulin therapy, have poor metabolic control and high HbA1c values. This is often due to increased insulin resistance, which requires high doses of insulin. Could the additional oral administration of metformin be an option?

  • Promising results of rituximab in systemic sclerosis

    The largest routine care study of rituximab use in systemic sclerosis (SSc) patients showed significant changes in skin fibrosis but not in lung fibrosis.

  • Mechanism found: Why neurodevelopmental disorders affect more males than females

    The study of mice, published in Nature Communications, led to the discovery that the O-linked N-acetylglucosamine transferase (OGT) molecule sets sex-specific patterns of gene expression.

  • Long-term exposure show that apremilast significantly improves PsA

    Apremilast has demonstrated sustained and clinically meaningful improvements in signs and symptoms of psoriatic arthritis, as well as in physical function in patients who continued treatment over 5 years.

  • Up to 42% of cancer cases could be preventable through lifestyle choices

    A large, ongoing USA study with over 1.5 million cases analyzed lifestyle factors on tumorous cancer risk. The findings hint at how many cancer cases could be prevented with simple lifestyle changes.

  • HIPEC without effect in colorectal peritoneal carcinomatosis

    Hyperthermic intraperitoneal chemotherapy in peritoneal carcinomatosis surgery does not improve survival and may increase the rate of complications compared to surgery alone.

  • Thousands of genes affected by DNA loop changes caused by the cancer-causing HTLV-1 virus

    New research exposes that the human leukemia virus (HTLV-1) disrupts the regulation processes of thousands of genes and changes intracellular DNA loops, raising the risk of a rare type of leukemia.

  • Rivaroxaban and ASA: The new dream team of CHD prevention?

    A combination therapy with aspirin and low-dose rivaroxaban appears to be more effective in the secondary prevention of cardiovascular events than aspirin monotherapy.

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