• Heart palpitations after partying? This is a serious matter

    Excessive salt and alcohol consumption can trigger unpleasant events. One of these is the little-noticed Holiday Heart Syndrome.

  • Assoc Prof. Vaghefi: AI helps predict cardiovascular risks in retina scan

    Associate Prof. Vaghefi discusses AI retina scan algorithms, how the retina can detect other health issues, and how the retinal tech was deployed in rural India.

  • JAK3/TEC blockade leads to long-term improvement in alopecia areata

    Ritlecitinib sustained efficacy in treatment up to month 36 without new safety signals. Patient-reported outcomes improved already after 3 months.

  • Abemaciclib: OS benefit in HR-positive / HER2-negative ABC still statistically insignificant

    Overall survival seems numerically longer with abemaciclib + NSAI in post-menopausal patients with HR-positive / HER2-negative advanced breast cancer.

  • Suntan still considered “healthy” by a majority of medical laypersons

    Skin cancer prevention campaigns remain unsuccessful, a survey of 17,000 people from 17 countries showed. Many myths regarding sun exposure still hold.

  • TILs identify patients with immunogenic triple-negative breast cancer

    Patients with TNBC with over 40% Tumour Infiltrating Lymphocytes in their tumour, respond well on neoadjuvant immune checkpoint blockade.

  • Early emollient use may reduce AD risk in infants

    Infants with high risk of atopic dermatitis that started an 8-week intervention with emollients directly after birth, had a significant risk reduction for AD.

  • Italy: "Doctor, what are you wearing?!"

    A statement by an Italian physician association president on "indecorous" physicians’ photos, opens a wider debate on professional decorum and dignity.

  • Only modest benefit of colon cancer screening with colonoscopy

    A one-time colonoscopy for screening entailed an 18% risk reduction of incidence in colorectal cancer (CRC) compared with no screening.

  • Men's health: Be aware, and don´t avoid!

    Studies confirm time and again that men tend to avoid visits to their physicians more often than women. Why is that?

  • Triple therapy improves PFS in aRCC versus dual therapy

    Cabozantinib/ nivolumab/ipilimumab improves progression-free survival versus dual nivolumab/ipilimumab in untreated advanced renal cell carcinoma.

  • Procalcitonin-based algorithm helps spare antibiotics in acute pancreatitis

    Both antibiotic use and days with antibiotic use could be markedly reduced with the help of a procalcitonin-based algorithm.

  • Nivolumab + ipilimumab: No improved survival in local RCC at high risk post-nephrectomy

    Phase 3 Checkmate 914 trial showed that the adjuvant treatment does not improve survival for stage II–III localised RCC, which has high post-nephrectomy risk.

  • A physician in Antarctica, "the ultimate adventure"

    In Antarctica, thirteen people are cut off from the world for nine months. Among them, a physician with heavy duties, yet in an extraordinary adventure.

  • Is early surgery an underestimated treatment in patients with limited CD?

    Early surgery might benefit Crohn's patients, but identifying exact patient groups who will benefit from early surgery requires prospective studies.

  • Adenoma detection rates augmented by AI in colonoscopy

    Compared to conventional colonoscopy, the addition of artificial intelligence entailed significantly higher detection and lower rates of missed adenomas.

  • Advanced melanoma: Tumour-infiltrating lymphocytes outperform ipilimumab

    Second-line treatment with TIL improves PFS compared with ipilimumab in patients with advanced, non-resectable stage III–IV melanoma.

  • Mirikizumab shows sustained maintenance of symptom remission in ulcerative colitis

    Symptom control maintenance after 40 weeks was investigated in mirikizumab responders after a 12 week induction therapy.

  • Combined TYK2/JAK1 inhibition shows promise in hidradenitis suppurativa

    Brepocitinib demonstrated significant efficacy in Hidradenitis Suppurativa Clinical Response (HiSCR) and flare reduction in hidradenitis suppurativa (HS).

  • Robotics in elderly care: When the machine needs a helping hand

    Which technologies are useful for nursing home residents? And how can they be designed to respect their needs and protect their dignity?

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