• Could uromodulin help to fight cystitis?

    Some people are better protected against UTIs because their bodies produce higher levels of uromodulin. A research team discovered how the helper protein works, with possible implications for UTI treatment and prevention.

  • 32% more men complain of reduced sex drive in 2019, compared to 2009

    A 10-years single-center study reported that substantially more men complain of reduced sexual desire than a decade ago. Conversely, fewer men complain of erectile dysfunction and premature ejaculation.

  • New urosepsis data from the SERPENS study

    New findings show that urosepsis is associated with lower mortality than sepsis derived from other sites, but if appropriate measures are not taken, 10-15% will develop a recurrent urosepsis.

  • Debate: Upfront cytoreductive nephrectomy or not?

    The EAU20 virtual meeting featured a thematic session looking at the controversy in renal cancer surgery considering the timing and necessity of cytoreductive nephrectomy.

  • Europe-wide decline in birth rate due to economic uncertainties

    The trend in continental birth rate falls is partly related to economic uncertainty, as demographers from the Austrian Academy of Sciences show using data from the European Demographic Data Sheet.

  • Immuno-oncology + tyrosine kinase inhibitors: their role in intermediate- and poor-risk mRCC

    Prof. Axel Merseburger reviewed the recent evidence testing immuno-oncology (IO) in combination with tyrosine kinase inhibitors (TKIs) in metastatic renal cell carcinoma (mRCC).

  • COVID-19 detected via highly diluted gargle samples

    Pharmacologists have succeeded in detecting minute amounts of the coronavirus SARS-CoV-2 using mass spectrometry in solutions with which COVID-19 patients gargled. The new method could serve as a supplement to previously used tests.

  • Docetaxel + hormonal therapy: improved prostate cancer PFS

    Adding docetaxel to antiandrogen treatment improves progression-free survival (PFS) in prostate cancer patients with prostate-specific antigen (PSA) relapse.

  • LUTS 2-year outcomes: Aquablation versus TURP

    Aquablation demonstrated a significantly lower rate of sexual dysfunction at the primary safety endpoint of 3 months compared with transurethral resection of the prostate (TURP), according to phase-3 data.

  • Infertility and testis cancer risk: causality or association?

    In his state-of-the-art lecture, Prof. Leendert Looijenga discussed the connection between infertility and testicular cancer1. Both molecular associations and putative causality were reviewed.

  • Robotic-assisted partial nephrectomy: better morbidity

    New findings from the large, multicentre IRON study demonstrate that robot-assisted partial nephrectomy (RAPN) is associated with lower morbidity and similar oncologic and long-term renal function outcomes compared with open partial nephrectomy (OPN).

  • PSMA PET-CT staging is 27% more accurate

    Labeled prostate-specific membrane antigen in PET-CT fusion was superior in specificity and sensitivity to conventional imaging in pre-treatment staging of intermediate and high-risk localized prostate cancer.

  • Assessing lower urinary tract symptoms in the neuro-urologic patient

    The neurological history from male LUTS patients or their partners is essential. Urologists should perform a careful physical exam and perhaps a referral to neurologists prior to any invasive or irreversible treatment.

  • Medical History: The “K” Syndrome

    A highly contagious disease breaks out in Italy and threatens to contaminate the whole of Europe. Sick people remain in isolation. Caregivers risk their lives to protect them in a world in crisis. This disease had nothing to do with the medical field.

  • KEYNOTE-436 trial: QoL is the same for both arms in mRCC

    The trial demonstrated a significant survival advantage for intermediate and poor-risk patients with metastatic renal-cell carcinoma who received pembrolizumab + axitinib as compared to those receiving sunitinib.

  • Understanding MIBC biology for novel treatment options

    Prof. Yohann Loriot discussed novel treatment options beyond immunotherapy, urging a better understanding of tumor biology towards identifying new targets and facilitating precision medicine.

  • Adofaragene firadenovec effective in BCG-unresponsive papillary NMIBC

    A study investigating nadofaragene firadenovec for high-grade, BCG-unresponsive non-muscle invasive bladder cancer (NMIBC) achieved encouraging, durable, high-grade, recurrence-free survival.

  • Reduced BCG frequency = faster NMIBC recurrence

    Reduction in the frequency of BCG vaccine instillations during induction and maintenance treatment for non-muscle-invasive bladder cancer results in earlier disease recurrence relative to a standard schedule.

  • Prostatectomy: R-LRPE better than LRPE for continence

    New findings from the first prospective, multicenter, randomized trial demonstrated improved continence for patients undergoing robotic-assisted radical prostatectomy as compared with conventional laparoscopic radical prostatectomy.

  • Interview: Prof. Dr. De Win on the link between porn consumption and erectile dysfunction

    Prof. Dr. De Win is an expert in Adolescent, Paediatric and Reconstructive Urology at the Department of Urology, Universitair Ziekenhuis, Antwerp, Belgium.

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