• Chronic lung disease: Air pollution impact is similar to a cigarette pack a day

    The results of an 18-year long-term study showed that ozone pollution significantly contributes to the accelerated development of pulmonary emphysema.

  • A 290 million-year-old Paget's disease case found?

    A lizard-like animal that lived in the Permian 289 million years ago suffered from a disease of bone metabolism similar to the Paget's disease in modern humans. This is by far the oldest known evidence of such a disease and the oldest indirect evidence of a viral infection.

  • Which genes have the greatest influence on diseases?

    Scientists from the Berlin Institute of Health and the Charité University Hospital in Berlin have specifically changed the control ranges of 20 disease-relevant genes. This enabled them to identify those changes that have the greatest influence on disease processes.

  • HIV infection increases cancer mortality

    HIV-positive cancer patients have a worse outcome with prostate cancer and breast cancer. Carcinomas progress more rapidly and cancer-related mortality also increases.

  • Improved motor learning through brain stimulation

    Motor learning takes place both during the active practice of new processes and in the breaks afterward. New research shows that the consolidation of practiced sequences already begins during short interruptions of practice and can be improved by brain stimulation.

  • Benefits of vacuum therapy in primary wound healing

    Surgical wounds close more frequently and faster, infections are rarer than with standard care. However, 23% of the data from completed studies are still not available.

  • Method for brain signal testing compared

    External measurements taken on the scalp allow conclusions to be drawn about the underlying nerve cell activity.

  • Restoring hair cells through proteins

    Researchers at John Hopkins University have identified a pair of proteins that control when hair cells form in mammalian ears, to great precision. The research team believes these proteins may help restore hearing in people with irreversible deafness.

  • International criteria catalogue for Lupus takes shape

    New SLE classification criteria intend to help patients with SLE to be recognized more quickly and to be treated more effectively.

  • Tattoos & medicine: The future becomes more colourful

    Tattoos could become interesting from a diagnostic point of view. Scientists have succeeded for the first time in developing tattoos that work like disease-indicating sensors.

  • Blindness prevention possible with lifestyle changes

    Timely lifestyle changes can protect people at high risk of age-related macular degeneration (AMD) from vision loss into old age. This is a key intermediate result of the European research project EYE-RISK.

  • A look at ethical problems in Virtual Reality

    Dr. Philipp Kellmeyer, a researcher at the Freiburg University Hospital (Germany), calls for more sensitive use of virtual realities in medicine and nursing.

  • Research team identifies early cellular disorder in Alzheimer's disease

    Overactive nerve cells in certain areas of the brain are considered an early symptom of Alzheimer's disease. For the first time, a team from the Munich Technical University (TUM) was able to elucidate the causes and mechanisms of this initial and important step.

  • Painkiller resistance in pancreatic diseases deciphered

    Severe and persistent pancreatic pain is difficult to treat because many painkillers do not work in this organ. In a recent study, a team has discovered the reason: A certain endogenous nerve messenger substance is present in the pancreas’ nerves in very high concentrations.

  • A look at the first blood test for celiac disease

    Researchers found that in people with celiac disease, following gluten ingestion, certain inflammatory molecules associated with clinical symptoms occur in the bloodstream. These recently discovered biomarkers are the basis for the blood test.

  • Metastatic castration-resistant prostate carcinoma: Positive results from Phase 3 study

    Therapy with olaparib prolonged PFS in severely pretreated patients with mCRPC and defective DNA repair mechanisms by approximately 4 months compared to enzalutamide or abiraterone therapy.

  • Defeating food allergies with gastrointestinal microbiota

    Food allergies can be caused by the absence of certain intestinal bacteria. Current study results show that the replacement of these intestinal bacteria could make a decisive contribution to the treatment of allergies.

  • Metastatic bladder cancer: Atezolizumab prolongs PFS in first-line therapy when added to chemotherapy

    The PD-L1 inhibitor atezolizumab, when added to chemotherapy, prolonged the progression-free survival of untreated patients with metastatic bladder cancer from 6.3 to 8.2 months compared to chemotherapy.

  • Metastatic breast cancer: CDK4/6 inhibitors prolong survival

    Additional treatment with abemaciclib or ribociclib may prolong survival in women with advanced hormone receptor-positive and HER-2-negative breast cancer.

  • Checkpoint inhibitors: Better response of MSI-H tumors and tumors with high TMB

    Tumors with mismatch repair deficiency (MMRD) or tumors with high tumor mutational burden (TMB) respond better to therapy with checkpoint inhibitors than tumors without these properties.

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