New data shows that the widely used sweetener sucralose can impair the response to PD-1-based immunotherapies in tumor patients, due to triggered changes in the gut microbiome.
A systematic review examines the question of whether targeted respiratory muscle training can influence the anti-reflux barrier and alleviate reflux symptoms.
Digital habits are disrupting sleep across Europe, especially among adolescents. Why this matters for stress, cognition, and long-term health.
The 2025 ERC Guidelines introduce significant evidence-based updates in cardiac arrest epidemiology and management. Dr Enrico Baldi outlines the most relevant changes for clinical practice.
A 32-year-old man develops unexpected erectile difficulties during his honeymoon. Investigations are normal. What is the real diagnosis?
In a European case series involving 12 children with acute hepatitis of unknown cause, pronounced CD8 T-cell infiltrates were found in the liver, along with SARS-CoV-2 proteins.
Recent evidence shows how erectile dysfunction, ejaculation disorders and low sexual desire profoundly affect men’s psychological wellbeing, shaping identity, self-esteem and quality of life.
What may seem questionable at first glance has a perfectly plausible explanation: the gut-brain axis as an important mediator between the enteric and central nervous systems.
New data from 2024–2025 show how polygenic risk scores may refine prostate cancer screening and risk stratification, improving early detection while raising important clinical and ethical challenges.
EAU SRH 2025 updates strengthen ED management with structured diagnosis, better PDE5 strategies and clarified testosterone use, highlighting ED as a key indicator of men’s health.
The holiday season brings heavier workloads, reduced staffing and emotional strain. For many clinicians, Christmas is not a break but an amplifier of burnout risk.
After two years in Bangladesh, a 35-year-old woman returns with fever, upper abdominal pain and weakness. Can you diagnose her condition?
Who benefits most from fruquintinib in metastatic colorectal cancer? A subgroup analysis of the FRESCO-2 study focuses on individuals with long overall survival.
A 54-year-old woman has back pain and a long-neglected breast lump. Her clinical journey will require more than a single decision, challenging the tumor board to choose the right steps at the right time.
Achalasia patients have higher risk of oesophageal cancer. A new study identifies oesophageal Candida infections as a possible cancer development risk factor.
Breast-cancer screening is entering a new phase. Mammography stays the cornerstone, while AI and MRI in dense breasts accelerate the move toward personalized screening.
From Halsted’s radical mastectomy to precision oncology, breast cancer treatments garnered science, suffering and progress, revealing how medicine learned to heal without dehumanizing.
New SRY-gene screenings by World Athletics for female athlete eligibility reopens a sensitive debate overlapping genetics, endocrinology, and ethics.
HER2-low has reshaped treatment strategy in HR-positive disease. DESTINY-Breast06 confirms that ADCs deserve an earlier role after CDK4/6 inhibition.
A teenager arrives at the ED with confusion and visual hallucinations. Negative labs and imaging complicate the search for the underlying cause.