• Improved risk stratification for high-risk NMIBC

    The response to intravesical Bacillus Calmette-Guérin treatment in patients with high-risk NMIBC could be predicted by molecular subtyping of the tumours.

  • Prostate cancer treatments reduce quality of life

    In the EUPROMS 2.0 study, all therapies for patients with prostate cancer, other than active surveillance, were associated with a reduced quality of life.

  • Evidence for prognostic stratification in N3 penile cancer

    Patients with N3 penile squamous cell cancer had a worse OS if they displayed extra-nodal extension in inguinal LNM or pelvic lymphadenopathy.

  • One more journey: Virtual Reality in palliative care

    Dr Charlotte Decher reports on how VR technology is improving palliative care and what opportunities it offers for people at the end of life.

  • Tips for physicians: Recognising and treating monkeypox

    Monkeypox is currently spreading worldwide. In the process, the virus may be adapting more to humans, and a majority of cases are sexually transmitted.

  • United Kingdom: Mysterious hepatitis in children

    A wave of mysterious hepatitis outbreaks in children is spreading worldwide. In the UK, a potential cause to these cases is being considered by scientists.

  • Atezolizumab may benefit ctDNA-positive patients with post-op MIBC

    Exploratory analyses hint that the adjuvant improved overall survival of patients with post-operative carcinoma who had a positive ctDNA status.

  • Does systematic biopsy add value to prostate cancer detection rate?

    In patients with suspected prostate cancer and positive (mp)MRI, targeted plus systematic biopsy did not perform better than targeted biopsy for its detection.

  • The human body in outer space

    If NASA is to send people to Mars, it needs to know the effects of a space flight on the human body. The perfect solution: comparing an astronaut in space with his twin brother on Earth.

  • Novel therapeutic targets for benign prostatic hyperplasia

    A large genome-wide association study revealed novel therapeutic targets for patients with benign prostatic hyperplasia (BPH) requiring surgery.

  • Darolutamide performs well across subgroups in mHSPC

    Darolutamide added to ADT and docetaxel improved the overall survival of patients with mHSPC, compared with a regimen of ADT, docetaxel, and placebo.

  • PSMA PET/CT cannot replace mpMRI for diagnosis of prostate cancer

    18F-DCFPyL PSMA PET/CT imaging did not demonstrate better accuracy than multiparametric MRI in diagnosing prostate cancer in a phase 3 trial.

  • Germany: Position paper on the WHO 2030 HPV target released

    Published together with the Hepatitis B & C Public Policy Association, the German Liver Foundation the paper calls in particular for the support of vulnerable populations.

  • Neoadjuvant hormonal therapy looks promising in high-risk prostate cancer

    Degarelix plus apalutamide outperformed degarelix alone in high-risk prostate cancer patients who were to receive radical prostatectomy.

  • Worse psychological symptoms in IBD patients with concomitant fibromyalgia

    The study also revealed an 8.7% fibromyalgia prevalence in IBD patients; higher than the prevalence in the general population of 2–3%.

  • Burnout: Emergency physicians worldwide at the limit

    In this interview, Dr. Abdo Khoury addresses a global survey revealed that 62% of emergency medicine staff have been diagnosed with burnout, and how this unfolded

  • Methenamine hippurate: Non-inferiority to antibiotics in recurrent UTIs

    The non-antibiotic preventive methenamine hippurate displayed non-inferiority to daily low-dose prophylactic antibiotics in women with recurrent UTIs.

  • SUI: Mini-slings non-inferior to standard mid-urethral slings

    Single-incision mini-slings were found to be non-inferior to standard mid-urethral slings in women with stress urinary incontinence (SUI).

  • High morbidity in pregnant lupus patients and their unborns

    Pregnancy in SLE have a 3-fold risk of fetal intrauterine growth restriction and 2-fold premature birth risk compared with healthy women.

  • Fewer complications with robotic surgery in renal cancer

    Less complication rates were observed with robotic surgery versus open surgery in patients with intermediate or high complexity renal tumours.

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