A recent cost-effectiveness analysis addressed the question of the appropriate age for the start and end of screening colonoscopies.
Liver transplantation is a rapidly developing field. Advanced technologies, like AI, will improve access, outcomes, and offer more personalized care.
Tafasitamab plus lenalidomide and rituximab outperformed lenalidomide plus rituximab and a placebo in patients with relapsed or refractory follicular lymphoma.
Auto-SCT did not improve mantle cell lymphoma with undetectable minimal residual disease outcomes after induction therapy.
Daratumumab plus lenalidomide had superior PFS outcomes vis-a-vis lenalidomide plus dexamethasone in frail patients with untreated MM.
Allo-SCT was more efficacious than standard-of-care in paediatric patients with sickle cell anaemia and abnormal cerebral artery velocities.
For VTE patients who needed extended anticoagulation, a reduced DOAC dose did not meet non-inferiority criteria for efficacy, compared to full DOACs.
Three novel mezigdomide-based triplet therapies seem tolerated and associated with anti-tumour activity in patients with relapsed or refractory MM.
Axicabtagene ciloleucel was associated with durable responses and long-term survival in relapsed or refractory indolent non-Hodgkin lymphoma.
A man in his 60s enters the ER after two fainting spells on the same day. The previous night he was woken up by severe palpitations. How to proceed?
Uproleselan + chemotherapy did not outperform chemotherapy alone for relapsed or refractory AML; but authors saw interesting trends in subgroups.
Daratumumab reduced progression to multiple myeloma and prolonged overall survival in patients with high-risk smouldering MM.
The investigational therapy GLPG5101 was associated with high response and a favourable safety profile in relapsed or refractory non-Hodgkin lymphoma.
Rilzabrutinib improved efficacy and QoL outcomes over placebo with a favourable safety profile among heavily pre-treated adults with immune thrombocytopenia.
Revumenib continued to display promising anti-tumour activity among patients with relapsed or refractory KMT2Ar acute leukaemia.
Hydroxyurea was associated to a reduction in clinical adverse events and improvements in haematological parameters in the phase 2 PIVOT trial.
Daratumumab plus VRd outperformed VRd alone in MRD-negativity rates for previously untreated multiple myeloma cases ineligible for transplant.
Adding blinatumomab to standard chemotherapy improved survival in paediatric patients with NCI standard-risk B-ALL at average or high relapse risk.
The French health authority updated its recommendations for improving HIV prevention and treatment. HereĀ“s an overview of the main points.
Despite the decline in new HIV infections in recent decades, UNICEF is concerned about the gender gap in HIV prevalence.