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Michael J. Peluso, University of California, San Francisco (USA), presented at the virtual CROI in March 2020 the largest case series to date of patients who developed early HIV infection under PrEP.
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Thanks to modern antiretroviral therapy, the life expectancy average of HIV-infected people has improved significantly. It is now only 3.3 years less than that of non-infected persons. However, many of them suffer from comorbidities.
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HIV-infected people often suffer from sleep disorders, which in turn increases the risk of a heart attack. An analysis of CNICS patient groups showed that patients with stressful insomnia increase the risk of type 2 myocardial infarction.
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In the ADVANCE study, treatment with dolutegravir+tenofovir alafenamide+emtricitabine was associated with a higher risk of obesity, metabolic syndrome, increase in visceral and subcutaneous fat, and long-term risk of developing diabetes.
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Metabolic complications are a major challenge of HIV infection and antiretroviral therapy (ART). Many of these complications are mediated by adipose tissue. Current knowledge on this topic was presented at the virtual CROI 2020.
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Long-acting antiretroviral therapeutics might be particularly suitable for patients who have problems swallowing, who fear stigmatization or who do not want to take medication every day.
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ROADMAP study showed that a kick-and-kill strategy with the HDAC inhibitor romidepsin and the bNAb 3BNC117 proved to be ineffective in 20 patients with chronic HIV infection under long-term ART.
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The effect of intramuscular administration of long-acting cabotegravir and rilpivirine is not inferior to monthly injections in maintenance therapy for patients with HIV infection, as found by the ATLAS-2M study.
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The Italian Society of Anesthesia, Analgesia, Resuscitation and Intensive Care (SIAARTI) has just published its clinical ethical guidelines for exceptional conditions, in the context of the Covid-19 epidemic.
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Men who have sex with men (MSM) are disproportionately affected by STIs, and HIV pre-exposure prophylaxis may play a role in their rise. Increasingly, STIs in MSM may be extragenital and asymptomatic.
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Antiretroviral therapies (ART) are enabling HIV+ people to have an almost unaffected life expectancy and the need for elderly care. Elderly HIV+ patients suffer from particular comorbidities that need to be addressed.
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Dr. Omar Alquati is a physician working at the Lodi Local Health Authority in Italy. He works in intensive care units but is currently a COVID-19 patient at Pavia's San Matteo Polyclinic. He shared his thoughts and experience since becoming infected.
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A new study, coordinated by a team from Siena University (Italy) has published findings on heavy metals concentrations in cancer patients’ blood, shedding light on the environmental implications of life in Italy’s “Land of Fire” in the Campania region.
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A private Facebook group for physicians is in the spotlight because of its excesses, including offensive comments against patients.
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Half of American general surgery residents (particularly women) experience abuse in the workplace. This significantly increases their risk of burnout and the prevalence of suicidal thoughts, according to a study.
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An overview of the ongoing trials and fresh knowledge that medicine has acquired on Huntington's disease was recently presented in Rome, Italy
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Male scientists seem to frame their research results in a more positive way than female scientists, regardless of the importance or novelty of these results.
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The administration of statins to decisively lower LDL levels in patients who have had a transient ischemic attack (TIA) or an atherosclerotic ischemic stroke reduces the risk of further severe cardiovascular events.
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The A13 antibody rejuvenates the brain by promoting the birth of new neurons and combating the defects that accompany the early stages of Alzheimer's disease. This opens up new possibilities for diagnosis and treatment.
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Many heart patients do not understand or remember the information provided before procedures. For example, patients mistakenly believe that Percutaneous Coronary Intervention cures them of heart disease.
