• Yeast: a possible antigen in Crohn's disease?

    Nutrition is believed to impact Crohn's disease. Yeast in particular and the body's own immune response to it could play an important pathophysiological role.

  • Medical Case: Acute abdominal pain in a young adult

    A 39-year-old man presents to the emergency department with acute abdominal pain, anaemia, and diarrhea: what diagnosis lies behind this condition?

  • Social media usage: how it affects students' sleep quality

    Social media use has raised alarms regarding addiction, and manipulative content. But their link to sleep problems was barely researched, until a 2023 study.<sup>1</sup>

  • Red Cross emblems: light and shadow

    From a red cross to a red crystal: how history, politics and faith shaped the world’s most iconic humanitarian emblems.

  • Medical Update: A treatment for drug-resistant epilepsy

    Drug therapy is ineffective in 30% epilepsy patients, who should be referred to specialised centres to evaluate available therapeutic alternatives.

  • Endometriosis in adolescence

    Timely diagnosis and personalized management of endometriosis in adolescents remain an urgent and unmet clinical need.

  • Medical Case: A long hospital stay with recurrent infections

    A 55-year-old woman suffers paraplegia, anemia, and recurrent infections. What is the underlying diagnosis?

  • Artificial intelligence (AI) in neurology

    AI offers advantages in terms of speed, accuracy, and data processing. But what implications for everyday clinical practice are we seeing already?

  • Myocarditis after COVID-19 and influenza

    What is the difference in the risk of myocarditis after SARS-CoV-2 and influenza infection? A new cohort study provides clear answers.

  • The benefit of a specific intervention for hospitalised patients with AKI

    Among patients with Acute Kidney Injury, recommendations did not significantly reduce the composite outcome of worsening AKI stage, dialysis or mortality.

  • Coeliac disease: healthy bones despite higher BMI and greater muscle mass

    Celiac disease is associated with higher osteoporosis risk. A recent study suggests that muscle mass, BMI and bone health may be linked in those affected.

  • Medical Case: An unexplained shortness of breath, and a surprising discovery

    An 82-year-old patient complains of severe shortness of breath and other symptoms, and the cause remains unclear at first. What could be behind these symptoms?

  • Fibrodysplasia ossificans progressiva, a rare genetic disorder

    FOP is a rare genetic disorder where soft tissues turn into bone, limiting movement and causing severe complications, with an average life expectancy of 40 years.

  • Rare diseases are no longer just a curiosity

    Rare diseases evolved from anomalies to recognized conditions, with key advances in genetics, treatment, and global initiatives.

  • Fabry disease in paediatric patients

    Pediatric FD poses a complex clinical challenge, with early symptoms, progressive multiorgan involvement, and diagnostic delays. Early diagnosis and intervention are key.

  • A chatbot that knows more than a doctor?

    A study shows that AI outperforms doctors in complex diagnoses. However, integrating it into medical practice requires more than just technology.

  • Neuroprosthetic communication in ALS

    An article published in the NEJM presents new technologies that could restore communication in ALS: a breakthrough for paralysed patients.

  • Antibiotics: risky during pregnancy and early childhood?

    The study used data from over three million children and focused on autism spectrum disorders, intellectual developmental delays, language development disorders and epilepsy.

  • How well do cancer drugs really work?

    Only a third of USA-approved oncology drugs seem to improve overall survival. This is the sobering conclusion of a retrospective analysis of US approvals.

  • PAT1 deficiency: the latest on the intestinal barrier and inflammatory bowel disease

    The deficiency of the anion transporter PAT1 leads to a disrupted intestinal barrier, microbial dysbiosis and increased susceptibility to intestinal inflammation.

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