• Menin inhibitors on the rise in KMT2Ar acute leukaemia

    Revumenib continued to display promising anti-tumour activity among patients with relapsed or refractory KMT2Ar acute leukaemia.

  • PIVOT: Can hydroxyurea improve outcomes in HbSC?

    Hydroxyurea was associated to a reduction in clinical adverse events and improvements in haematological parameters in the phase 2 PIVOT trial.

  • CEPHEUS: Further support for daratumumab-regimens in untreated MM

    Daratumumab plus VRd outperformed VRd alone in MRD-negativity rates for previously untreated multiple myeloma cases ineligible for transplant.

  • New standard-of-care for paediatric B-cell ALL

    Adding blinatumomab to standard chemotherapy improved survival in paediatric patients with NCI standard-risk B-ALL at average or high relapse risk.

  • HIV in France: Updated recommendations from the National Health Authority

    The French health authority updated its recommendations for improving HIV prevention and treatment. Here´s an overview of the main points.

  • AIDS hits young girls particularly hard worldwide

    Despite the decline in new HIV infections in recent decades, UNICEF is concerned about the gender gap in HIV prevalence.

  • ASH 2024: AI and innovative therapies are shaping the future of haematology

    The 66th Annual Meeting of the American Society of Hematology this December is a crucial forum on the latest advances in haematology.

  • Ultra-precision: the Institut Curie uses AI to improve prostate cancer detection

    Artificial intelligence is revolutionising cancer diagnosis, as the Institut Curie steps up its collaboration with Ibex Medical Analytics for post-stroke cancers.

  • Cognitive impairment in rheumatoid arthritis

    New research shows that RA increases the risk of cognitive impairment. Those affected particularly show deficits in memory and executive functions.

  • Vegan food can also be bad for the heart

    For many, a plant-based diet equals health. But is this always so? One study examined ultra-processed, purely plant-based foods' effects on the heart.

  • Therapy options for glioblastoma

    Glioblastoma is an extremely aggressive brain tumour, despite various therapeutic approaches, with a mostly poor prognosis. Which treatment is recommended?

  • EADV 2024 Congress: New perspectives on melanoma

    Recent advances in melanoma diagnosis and treatment emphasise the importance of new biomarkers for early detection and innovative therapies for advanced melanoma.

  • Tamuzimod delivers promising long-term data in ulcerative colitis

    Tamuzimod improved clinical, endoscopic, and histologic outcomes compared with placebo in moderately to severely active UC at week 52.

  • Upadacitinib associated with normalisation of HRQoL in UC

    Upadacitinib induction and maintenance therapy were associated with higher rates of normalisation of health-related quality-of-life (HRQoL) than placebo.

  • TL1A inhibitor tulisokibart shows potential in ulcerative colitis

    Tulisokibart displayed durable improvements in clinical and endoscopic outcomes in patients with moderately to severely active ulcerative colitis.

  • New insights into perianal fistulising CD pathogenesis may lead to new therapeutics

    Perianal fistulising Crohn’s disease was associated with increased IFN-γ expression and response in fistula tracts and luminal mucosa.

  • Exploring zibotentan plus dapagliflozin for cirrhosis

    Data from the cirrhosis subpopulation in the ZENITH-CKD trial suggest that the zibotentan and dapagliflozin combination may benefit liver health.

  • Cendakimab meets primary endpoints in eosinophilic oesophagitis

    Cendakimab outperformed placebo in patients with eosinophilic oesophagitis (EoE) across various efficacy endpoints in a phase 3 study.

  • Tradipitant improves symptoms of motion sickness

    Tradipitant successfully reduced nausea and vomiting associated with motion sickness in a clinical trial. Both low dose and high doses were well-tolerated.

  • Diagnostic accuracy of fluorescence confocal laser microscopy after EUS-TA

    Fluorescence confocal laser microscopy may allow real-time tissue diagnosis from solid pancreatic lesions, via an endoscopic ultrasound procedure.

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