Data demonstrate that the anti-CD40 colitis model shows key features of IBD observed in the human disease, hence making it a suitable model to investigate the pathophysiology of ulcerative colitis (UC).
Who thinks instantly of bowel cancer when abdominal pain or diarrhoea hits? It turns out, these complaints may be key symptoms of early colorectal cancer.
A preclinical study highlights the potential of SIWA318H, an antibody targeting advanced glycation end-products, in the fight against pancreatic cancer.
This review outlines the current management of pancreatic cancer, and the recent advances in its treatment. The review discusses future treatment pathways aimed at integrating novel findings of translational and clinical research.
The acute aspirin challenge significantly increased intestinal permeability similarly in both groups, and prophylactic probiotic consumption was unable to prevent the loss in this particular model.
The burden of perianal disease and perianal surgery rates were high in this cohort. Therapeutic strategy was accelerated in patients with perianal Crohn's over time with higher exposure to immunosuppressives and biologics.
In this study, we developed a new luminal stimulation modality to specifically activate these gastric stretch receptors to elicit a vagal afferent response commensurate with mechanical distension.
Helicobacter pylori, a dominant member of the gastric microbiota, shares co-evolutionary history with humans. This has led to the development of genetically distinct H. pylori subpopulations associated with the geographic origin of the host and with differential gastric disease risk.
Is Agent Orange (AO) exposure during the Vietnam War (1966 to 1975) associated with incident hepatocellular carcinoma (HCC)? These findings suggest that AO exposure is not associated with incident HCC.
This systematic review and meta-analysis of inflammatory bowel disease in Oceania found high incidence rates (19.8 [95% confidence interval, 15.8-23.7] per 100 000 person-years) and prevalence rates (303.3 [95% confidence interval, 128.1-478.4] per 100 000 persons).
The terms non-alcoholic fatty liver disease and non-alcoholic steatohepatitis are misleading for some experts, with inaccurate associations leading to stigmas.
An altered gut microbiome may precede the clinical signs of Alzheimer's disease. Can the gut microbiome be used as an early biomarker?
Patients after MBS should be advised about the risks while fasting including abdominal pain, dehydration, and peptic ulcer disease exacerbation, and a thorough review of their medications is warranted to minimize complications.
FCSEMS placement is an effective method in biliary strictures in case of PCC. Acute cholecystitis is encountered frequently after FCSEMS, but majority of patients respond to the medical treatment.
For the purpose of this review, we focused on the diagnosis of some of the most common inflammatory and structural pouch disorders and their respective management. Pouchitis is the most common complication, and it is typically responsive to antibiotics.
The CDED has emerged as a valid alternative to EEN with cumulative evidence, including randomized controlled trials, supporting use for induction of remission and possibly maintenance in children and adults.
There are several timely, important, and novel aspects to colorectal cancer (CRC) screening that are highlighted in the study by Aziz et al.
During a mean follow-up of 14.13 ± 3.98 years, 910 and 215 participants developed HNC and OAC, respectively. UPF consumption was positively associated with accidental death in the negative control analysis.
Gut microbiota plays a key role in insulin resistance (IR). Here we perform a case-control study of Chinese adults (ChiCTR2200065715) and identify that Parabacteroides distasonis is inversely correlated with IR.
The annual international congress took place as a hybrid event in Copenhaguen and online during 14-16 October with over 11,000 participants.