• Editorial: Underwater endoscopic submucosal dissection for colorectal tumors: the next step in the “underwater evolution”?

    A key advantage of underwater endoscopic mucosal resection is the rapid dissipation of thermal energy during the application of electrocautery for resection of polyps.

  • A yogurt drink instead of a colonoscopy? Study uses engineered bacteria to detect cancer

    A proof-of-concept study shows that DNA-slurping bacteria can identify cancerous sequences, advancing hope of a gentler form of diagnostics.

  • Is vaccination against COVID-19 associated with inflammatory bowel disease flare?

    The self-controlled Case Series Analysis using the UK CPRD investigated the association between vaccination against coronavirus disease 2019 (COVID-19) and inflammatory bowel disease (IBD) flare.

  • Use of lorazepam and survival outcomes for patients with pancreatic cancer

    A retrospective study investigating the impact of palliative care medicine on the tumor microenvironment has found that patients with pancreatic cancer who were prescribed the benzodiazepine lorazepam while undergoing chemotherapy had shorter progression-free survival than those patients who did not receive the benzodiazepine.

  • All-or-nothing behavior and catastrophic thinking predict fatigue in inflammatory bowel disease: a prospective cohort study

    In this study of people with IBD, we demonstrate that all-or-nothing behavior (being very active then needing to resting a while) and catastrophic thinking (making very negative assumptions about outcomes) both predict worsening in fatigue over time.

  • New blood test could ‘transform’ treatment for children with fever

    Doctors say test may diagnose childhood illnesses in less than an hour, helping quickly identify life-threatening infections

  • Long-term therapy of hepatits B with NUCs: obstacle to functional cure?

    Ending long-term therapy of HBeAg-negative hepatitis B with NUC was believed to induce a functional cure. Data on this was very limited, until a new study.

  • Interview: The role of the microbiome in haematology

    The microbiome is crucial for immunity, metabolic homeostasis, and protection from pathogens. What about its role in haematological diseases?

  • New hopes for chronic inflammatory bowel diseases?

    Two recent studies look at the efficacy of mirikizumab and upadacitinib in ulcerative colitis and Crohn's disease. Can IBD patients benefit?

  • Milk as a superfood: A debunked myth?

    Many humans cannot tolerate cow's milk, yet the dairy industry is huge. Prof. Renneberg shares memories and histories about lactose intolerance.

  • Meditation: important for a healthy bowel?

    Meditation is a millennia-old practice for training the mind and body. It also has a positive effect on physical and mental health. But what is the reason for this?

  • Polypectomy: repeated colonoscopies are not necessary

    For a successful polypectomy, a good colonoscopy is the key. The procedure should only require one colonoscopy, but many undergo several. Improvement is much needed.

  • Microbiome: what role does it play in depression and its treatment?

    New studies link the gut microbiome to depressive disorders. This may result in a new therapeutic approach for affective disorder treatments.

  • Updates on coeliac disease diagnosis in children

    A free, online decision-making algorithm helps physicians with diagnosis, evaluation and treatment for coeliac disease management in pediatrics.

  • Is the long-term use of PPIs problematic?

    A long-term study of 20,000 people with type 2 diabetes reported that long-term use of PPIs is associated with increased cardiovascular and mortality risks.

  • Malnutrition in cancer patients increases risk of surgery

    Tumour patients often suffer from malnutrition, as gastric cancers drain nutritional supplies. Research on this was limited until a new large-scale global study.

  • Localised colon cancer: better outcomes with neoadjuvant chemotherapy

    There was little data on whether neoadjuvant chemotherapy benefitted in advanced but localised colon cancer. This changed due to a recently published study.

  • Oxidative stress in sleep deprivation: probiotics can help

    Many people suffer from lack of sleep or sleep deprivation. The resulting oxidative stress can have a cell-damaging effect. A recent study tested probiotics' role for this.

  • Errors in colonoscopy and how to avoid them

    Colonoscopy is complex, and endoscopy errors can occur. Targeted consideration of technical and non-technical skills can reduce avoidable errors and increase patient safety.

  • TACE: Transarterial chemoembolisation for hepatocellular carcinoma

    Local interventional procedures are being used in primary and secondary liver tumours. How does transarterial chemoembolisation work in HCC?

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