Could bacteria or viruses be rendered harmless by tomatoes or its products? Researchers investigated if tomato substances work against S. typhi.
Precision medicine is revolutionising treatments for colon cancer and other gastrointestinal malignancies by identifying biomarkers for personalised therapies.
Gastrointestinal biofilms are highly heterogenic and spatially organized polymicrobial communities that can expand and cover large areas in the gastrointestinal tract.
Glycolysis in HSCs amplifies liver fibrosis by promoting fibrogenic EV release in the hepatic pericentral zone, which represents a potential therapeutic target.
The practice of routine UGI endoscopy before elective cholecystectomy has been justified by the finding of active UGI pathology which warranted treatment in a significant proportion of patients with presumed symptomatic gallstones in an African setting.
In this diagnostic study validating a prediction model, the model demonstrated excellent accuracy. At a score of at least 6 points, prediction model accuracy and performance were optimized, serious alternative diagnoses were uncommon, and diagnostic yield of early imaging was low.
This systematic review and meta-analysis suggests that there is an increased risk of SIBO in patients with IF and that PN, and potentially, the use of PPI/acid-suppressing agents is risk factors for SIBO development in patients with IF.
The prevalence of MASLD was greater among food-insecure adolescents vs food-secure ones (17.4% vs 9.4%) and adolescents living with a low HH income vs those with a higher HH income (15.0% vs 7.2%) and living with a head of HH with a lower education level vs one with a higher education level (18.0% vs 8.2%) (P < 0.05).
Our data support the murine model to study OCTN1 genetic contribution to inflammatory bowel diseases. This could be the first step towards the recognition of this membrane transporter as a biomarker in inflammatory conditions and a predictor of response to therapies.
The intestinal microbiome is essential in many body processes. Could prebiotic food intake benefit intestinal flora in intestinal polyps or colorectal carcinoma?
Gastro-oesophageal reflux and regurgitation often cause parental concern, but only few babies have a pathology that requires treatment.
There was evidence for a reduction in recurrent bleeding from peptic ulcers with adherent clots treated with endoscopic hemostatic techniques compared with medical management alone but no difference in rates of mortality or need for surgery.
This Review discusses the future requirements for intelligent capsule robots, providing a comparative evaluation of various methods’ merits and disadvantages, and highlighting recent developments in six technologies relevant to WCE.
The findings of this cohort study indicate that a high genetic risk of GC may be counteracted by H pylori treatment, suggesting primary prevention could be tailored to genetic risk for more effective prevention.
Among the four noninvasive models, GPR has the best performance in the diagnosis of hepatic fibrosis in CHB patients and is more valuable in HBeAg-positive patients.
Clinical, endoscopic, genetic, pathological data from patients with SMAD4 or BMPR1A PVs included between 2007 and 2020 in the French network on rare digestive polyposis (RENAPOL) database were prospectively collected to address uncertainties regarding gastric involvement.
UEMR has superior vertical resectability compared with CSP, but CSP has a shorter procedure time and fewer bleeding events. Although CSP is preferable for most small SNADET, UEMR should be selected for lesions that cannot be definitively diagnosed as mucosal low-grade neoplasias.
Overall, proliferating activated HLA-DR+CD38+ effector Th1/17 cells distinguish CD-associated from cryptoglandular perianal fistulas and are a promising biomarker in blood to discriminate between these 2 fistula types.
Some Crohn's disease or ulcerative colitis patients do not respond to infliximab or its effect diminish for them. This could be related to visceral fat mass.
It doesn't have to be manifest diabetes. Even slightly elevated glucose levels over several years are enough to increase the risk of gastrointestinal cancer. This is the result of a population study from South Korea.