In the Asia region, a correlation between high salt consumption and stomach cancer has been established. This is now confirmed in European cancer statistics.
Poor dietary intake with nutritional deficiency and overweight have been described to increase the risk of IBS. The aim of the present study was to compare weight and circulating levels of micronutrients in IBS compared with healthy controls.
Little is known about patterns of opioid prescribing in inflammatory bowel disease (IBD), but pain is common in persons with IBD. We estimated the incidence and prevalence of opioid use in adults with IBD and an unaffected reference cohort and assessed factors that modified opioid use.
Patients with ulcerative colitis (UC) receiving immunosuppressive drugs are at substantial risk of colectomy. We aimed to assess the risk of postoperative complications of tofacitinib exposure before colectomy in comparison with biologics.
This study provides evidence that there is a common genetic architecture unique to asthma and GERD that may explain comorbidity and requires further investigation.
Early-onset colorectal cancer (EO-CRC; defined as colorectal cancer [CRC] diagnosed in individuals younger than 50 years) has increased recently in the US.1 Evidence has shown that patients living in impoverished and rural areas have an increased risk of CRC death,2,3 but this has not been examined for EO-CRC.
Here we report a fundamental liquid sampling mechanism that enables millimeter-scale soft capsules for sampling liquids in confined spaces. The miniature capsule is enabled by flexible magnetic valves and superabsorbent polymer, fully wirelessly controlled for on-demand fluid sampling.
Research reveals a previously unknown mechanism that triggers cachexia, a muscle weakness condition common in pancreatic cancer patients.
This study aimed to compare the determinants and impact of hepatocellular carcinoma (HCC) surveillance rates for people with metabolic dysfunction-associated steatotic liver disease (MASLD) versus other chronic liver diseases.
A recent study investigated if niacin (vitamin B3) intake can reduce the general and cardiovascular mortality of those affected by NAFLD
Accurate risk prediction can facilitate screening and early detection of pancreatic cancer (PC). We conducted a systematic review to critically evaluate effectiveness of machine learning (ML) and artificial intelligence (AI) techniques applied to electronic health records (EHR) for PC risk prediction.
In vitro, CD84 promoted alcohol-induced interleukin-1β and tumor necrosis factor–α in primary human neutrophils, which was inhibited by CD84-blocking antibody treatment. Our findings define the role of BTK and CD84 in regulating neutrophil inflammation and granulopoiesis, with potential therapeutic implications in AH.
A low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet was also shown to decrease symptoms in patients with quiescent or mildly active CD (high risk of bias), however, this was not corroborated by other low FODMAP diet studies.
A 72-year-old woman was presented to the emergency department with the primary complaint of severe epigastric pain lasting 1 day. The patient's medical history was notable for hypertension for 30 years and cholecystolithiasis diagnosed 1 year prior.
Multistrain probiotics did not reduce the incidence of MDRO+ colonization at day 30 of life in preterm infants but modulated their microbiome toward eubiosis.
Mirikizumab treatment significantly improved fatigue in patients with moderately to severely active CD, which was sustained to W104. The improvement in fatigue was correlated with improvement in clinical measures and was strongly correlated with improvement in QoL.
Although microbial pathogens were not prevalent, we found several MAGs harboring genes related to antibiotic resistance, highlighting that dairy industry surfaces represent a potential hotspot for antimicrobial resistance (AR) spreading along the food chain.
This interview after the 'ESMO GI Cancers 2024' congress was an opportunity for in-depth study and discussion of new developments in GI oncology.
Gastrointestinal tumours occur most frequently in people over 70. But how does the treatment of geriatric patients differ from that of younger patients?
Long-term daily aspirin intake may help prevent colorectal cancer development and progression but the mechanisms involved are still unclear.