In cases of malignant colonic obstruction (MCO), self-expandable metallic stents (SEMS) are used as a bridge to surgery, offering an alternative to emergency surgery. However, the long-term oncologic outcomes remain debated, particularly in developing countries where the cost of SEMS is a concern.
The purpose of the present study was to establish a prognostic model of CRGs and provide directions for the diagnosis and treatment of GC. Transcriptome and clinical data of patients with GC were collected from The Cancer Genome Atlas and Gene Expression Omnibus datasets.
Selenium deficiency is a common find in inflammatory bowel diseases. Recent studies emphasise that there is a benefit in selenium intake for these patients.
Primary sclerosing cholangitis (PSC) may reoccur following liver transplantation (LT), and the diagnosis established once imaging studies demonstrate the diagnostic cholangiographic appearance. To evaluate whether the development of recurrent PSC (rPSC) is associated with cholestasis soon after LT, we studied whether changes in hepatic biochemistry within the first 12 months were linked with the development of rPSC and graft loss.
Circulating albumin concentrations are frequently measured in clinical practice. This review explores biochemical properties and physiological roles of albumin, its place in nutritional assessment, current understanding of perturbed circulating concentrations, and role in clinical management, with special focus on patients with inflammatory bowel disease (IBD).
Persons with inflammatory bowel disease exhibit a weaker relationship between executive function and functional connectivity of cerebellar regions (VIIa Crus I and VIIa Crus II) to cortical areas involved in visual processing compared to healthy counterparts with comparable performance.
In this randomized clinical trial that included 1254 adults, the AQCS-assisted group achieved a significantly higher adenoma detection rate vs the standard colonoscopy group (32.7% vs 22.6%).
GABD continue to pose a significant global public health challenge, particularly affecting women and the elderly population. Consequently, the implementation of effective interventions to mitigate the GABD burden is of paramount importance.
We analyzed a nationwide sample of United States Medicare beneficiaries hospitalized from 2017-2019 for common gastrointestinal diseases, grouped by Diagnosis Related Groups (DRGs).
Patients with ulcerative colitis (UC) and prior biologic failure may have reduced or delayed efficacy with subsequent advanced therapies. This analysis evaluated the efficacy and safety of ozanimod during the True North (TN) study and its open-label extension (OLE) in biologic-exposed patients with UC.
A recent cost-effectiveness analysis addressed the question of the appropriate age for the start and end of screening colonoscopies.
This study demonstrates a negative association between daily sodium intake and constipation risk among adult males, suggesting that sodium intake might influence intestinal function.
“PolynetDWTCADx” is a sophisticated hybrid model that was developed to identify and distinguish colorectal cancer. In this study, the CKHK-22 dataset, comprising 24 classes, served as the introduction.
Pregnancy with a stoma is feasible, though manageable complications often occur. Counseling before pregnancy and close monitoring of symptoms during pregnancy and postpartum are essential for women with IBD and a stoma.
This standardized approach provides clear and consistent portion recommendations that, if adopted, could help consumers make informed choices about appropriate portions.
Liver transplantation is a rapidly developing field. Advanced technologies, like AI, will improve access, outcomes, and offer more personalized care.
Optimal endoscopy timing becomes even more complicated when taking into account the higher probability of mortality in the elderly presenting with UGIB. The current study aimed to evaluate the optimal endoscopy time in elderly patients based on clinical outcomes.
Tamuzimod improved clinical, endoscopic, and histologic outcomes compared with placebo in moderately to severely active UC at week 52.
Upadacitinib induction and maintenance therapy were associated with higher rates of normalisation of health-related quality-of-life (HRQoL) than placebo.
Tulisokibart displayed durable improvements in clinical and endoscopic outcomes in patients with moderately to severely active ulcerative colitis.