• Impacts of salt restriction on nutritional status, sarcopenia, and mortality of cirrhotic patients with ascites

    While effective in ascites control, sodium restriction may compromise nutritional status, heighten sarcopenia risk, and increase mortality, highlighting the need for a more individualized dietary approach.

  • Salivary pepsin: a marker for reflux cough

    A simple saliva test outperforms the standard questionnaire for reflux cough with 83.6% accuracy. The pepsin test demonstrates its superiority particularly in cases of non-acid reflux.

  • The Helicobacter pylori AI-clinician harnesses artificial intelligence to personalise H. pylori treatment recommendations

    Here, we develop a reinforcement learning-based AI Clinician system to personalise treatment selection and evaluate its ability to improve eradication success compared to clinician-prescribed therapies.

  • Feasibility and Safety of Small Bowel Capsule Endoscopy in Very Early-Onset Inflammatory Bowel Disease: A Multi-Institutional Study

    Small bowel capsule endoscopy is a valuable modality for evaluating small intestinal lesions in children with inflammatory bowel disease. However, its application for very early-onset inflammatory bowel disease remains insufficiently documented.

  • Mediterranean diet score linked to cognitive functioning in Czech women: a cross-sectional population-based study

    The evidence suggests that adherence to the Mediterranean diet (MD) may be beneficial in preventing cognitive decline. We aimed to explore this association in a Central European population.

  • ACG Clinical Guideline Update: Preventive Care in Inflammatory Bowel Disease

    Patients with inflammatory bowel disease (IBD) often consider their gastroenterologist to be the primary provider of care. To improve the care delivered to patients with IBD, health maintenance issues need to be addressed by the gastroenterology team.

  • Oral Vancomycin for Prevention of Recurrent Clostridioides difficile Infection

    In this randomized clinical trial of 81 participants who had completed treatment for a CDI and were taking systemic antibiotics for a non-CDI indication, recurrent CDI occurred in 43.6% of participants in the oral vancomycin group vs 57.1% in the placebo group at 8 weeks. However, the study was underpowered and this difference did not reach statistical significance.

  • The rising burden of gastrointestinal cancers

    A group of experts from ESMO GI 2025 highlight critical trends and new therapeutic strategies to address the global increase in gastrointestinal cancers.

  • Association between gastrointestinal symptoms and insomnia among healthcare workers: a cross-sectional study

    Although research has established that stress and shift work are independent risk factors for gastrointestinal discomfort and insomnia, the direct link between these two conditions in healthcare workers remains insufficiently explored.

  • “Insert-Coin”: A Prospective Study of Coin Ingestion in Children of Southern Italy

    Coins are the most commonly ingested foreign bodies. When they get stuck in the distal esophagus, there is no general agreement about the timing of their removal because some of them may spontaneously migrate into the stomach, no longer requiring removal. We aimed at evaluating the gastric spontaneous passage of esophageal-retained coins, as well as complications.

  • The Association of Inflammatory Bowel Disease and Eosinophilic Esophagitis: A Systematic Review and Meta-analysis

    The association between inflammatory bowel disease (IBD) and eosinophilic esophagitis (EoE) remains unclear. We aimed to perform a systematic review and meta-analysis on the association between EoE, IBD, and other immune-mediated inflammatory diseases.

  • Accuracy of Artificial Intelligence for Gatekeeping in Referrals to Specialized Care

    In this diagnostic study of an AI model for gatekeeping that was developed, tested, and validated sequentially, the model differentiated between referrals that warranted immediate authorization and additional information with moderate accuracy and outperformed human gatekeepers by nearly 20%, primarily due to increased specificity.

  • Trends in incidence and mortality of early-onset gastrointestinal cancers: a comprehensive study

    Early-Onset Gastrointestinal Cancers concerns tumors in people under 50. Accumulating evidence suggests a significant increase in the burden of colorectal cancer in young adults. We investigated the global burden and spatiotemporal trends of the 6 major gastrointestinal (GI) cancers.

  • Efficacy and safety of Saccharomyces boulardii as adjunct therapy with Vancomycin in treating Clostridioides difficile infection: A randomized controlled trial

    Clostridioides difficile infection (CDI) is a significant cause of hospital-acquired diarrhea, leading to high morbidity, recurrence, and healthcare costs. Probiotics like Saccharomyces boulardii show potential as an adjunct therapy to standard CDI treatment, but further trials are needed to confirm their efficacy.

  • Ascites without cirrhosis: finding differential diagnoses and treating correctly

    Ascites is often equated with cirrhosis of the liver, but the causes can be much more diverse – ranging from malignant diseases and infections to rare syndromes.

  • Differences in Clinical Characteristics Between Missed and Detected Laryngopharyngeal Cancers

    Laryngopharyngeal cancers are often overlooked during endoscopy because of their anatomical complexity and the gag reflex. However, the characteristics of these cancers remain poorly understood.

  • Worldwide increase in early-onset colorectal cancer: New data and clinical implications

    In over half of countries studied, incidence is increasing among young adults, often in contrast to stable or declining rates among older patients.

  • A New Drying Method of Thermolabile Flexible Endoscope Channels by Laminar and Turbulent Airflow: A Prospective, Randomized-Controlled, Single-Center, Proof-of-Concept Trial

    The aim of this study was to compare the drying cycle of a standard endoscope washer-disinfector (EWD) (standard drying method [SD]) with a shortened mandatory drying by the EWD followed by a special drying device using laminar and turbulent air flow (novel drying method [ND]).

  • Diet-induced inflammation is associated with fatty pancreas in patients with common bile duct stones

    Inflammation has been proven to be associated with chronic diseases. We hypothesized that higher diet-induced inflammation is associated with increased risk of fatty pancreas (FP).

  • Global burden of colon and rectal cancer and attributable risk factors in 204 countries and territories from 1990 to 2021

    Using updated data from the Global Burden of Disease (GBD) 2021 study, this research explores the national-level spatial distribution of CRC burdens linked to key risk factors and analyzes temporal trends in their contributions.

  • 1 |
  • 2 |
  • 3 |
  • 4 |
  • 5 |
  • 6 |
  • 7 |