• Ultra-processed foods and cardiometabolic health: public health policies to reduce consumption cannot wait

    Existing evidence is sufficiently strong to warrant immediate public health actions to help citizens identify ultra-processed foods and limit their exposure.

  • Depression symptoms increase the risk for initiation or switching to biologic therapy in pediatric inflammatory bowel disease patients in remission

    Mental health screening programs should be incorporated in routine clinical practice, especially for depression, regardless of disease activity and disease type.

  • Intelligent surgical workflow recognition for endoscopic submucosal dissection with real-time animal study

    Here we propose AI-Endo, an intelligent surgical workflow recognition suit, for endoscopic submucosal dissection (ESD). Our AI-Endo is trained on high-quality ESD cases from an expert endoscopist, covering a decade time expansion.

  • Statin therapy for liver protection?

    More people are developing liver damage or liver carcinoma. Can the rising number of deaths caused by these be reduced? Statins may be an option.

  • Eosinophilic oesophagitis: the milk does the trick

    Eliminating certain foods can help cure eosinophilic oesophagitis. But it is often unclear which to eliminate or abstain from. Researchers compared elimination diets of different foods, versus those where only cow's milk was avoided.

  • Proton-pump inhibitors and cancer therapy: a bad combination?

    Some retrospective studies suggested that combination of PPIs with immuno-chemotherapies, is associated with worse outcomes. What's new on this issue?

  • Significant Dose-Response Association of Physical Activity and Diet Quality With Mortality in Adults With Suspected NAFLD in a Population Study

    Analyses revealed a dose-dependent, nonlinear association of PA (volume and intensity) with all-cause mortality and a dose-dependent, linear association of DQ with all-cause mortality.

  • STAR SIGN study: Evaluation of COVID-19 vaccine efficacy against the SARS-CoV-2 variants BQ.1.1 and XBB.1.5 in patients with inflammatory bowel disease

    Surrogate neutralisation against all tested sublineages was reduced in patients with IBD who were treated with anti-TNF biologics compared to patients treated with non-anti-TNF biologics and healthy controls.

  • Can balloon-assisted enteroscopy predict disease outcomes in patients with small-bowel Crohn’s disease?

    The present study demonstrated the role of BAE in the endoscopic assessment of disease activity and its predictive value for the risk of surgery in small-bowel CD patients. Further optimization of BAE utilization for the assessment of disease activity is warranted in clinical practice.

  • Global prevalence of psychological distress and comorbidity with disorders of gut-brain interactions

    Clinically relevant psychological distress and/or somatic symptom severity was reported by 37.5% of the sample. These participants had 4.45 times higher odds to have at least one DGBI than individuals without psychological distress and/or somatic symptoms.

  • NET: What gastroenterologists should know

    Even gastroenterologists may struggle with this very special and heterogeneous group of neoplasms. But a correct diagnosis is usually within their grasp.

  • Vitamin D and Early-Onset Colorectal Cancer—Rays of Hope?

    Vitamin D deficiency may be a risk factor for early-onset CRC, and findings suggest that ensuring vitamin D sufficiency through supplementation may be particularly important for the prevention of early-onset CRC.

  • Study on the factors influencing the prognosis after perianal abscess surgery

    Preoperative assessment of the abscess range and precise intraoperative methods to resolve the infection of the abscess glands in the internal mouth can effectively improve the cure rate.

  • China’s Fatty Liver Crisis: A Looming Public Health Emergency

    Using published cutoffs, the authors estimated that 44.4% of the study population had fatty liver, 2.9% had advanced fibrosis, and 0.87% had cirrhosis.

  • Obesity: can a healthy gut microbiome contribute to treatment?

    If the intestinal microbiome is unbalanced, chronic diseases or micro-inflammations often ensue. What role does intestinal flora dysfunction play in grade III obesity?

  • Medical Case: Patient with diarrhoea and lower abdominal pain

    A 20-year-old woman arrives to the emergency room with lower abdominal pain and changes in bowel movements. What is your probable diagnosis?

  • Surgery for gastrointestinal tumours: Could AI take over soon?

    Artificial intelligence has also arrived in the operating room. Will it replace surgeons in the future?

  • Antibiotics promote intestinal growth of carbapenem-resistant Enterobacteriaceae by enriching nutrients and depleting microbial metabolites

    Antibiotic-induced reduction of gut microbial populations leads to an enrichment of nutrients and depletion of inhibitory metabolites, which enhances CRE growth.

  • Gut microbiota and fecal short chain fatty acids differ with adiposity and country of origin: the METS-microbiome study

    Diabetes, glucose, and hypertension are only predictive in certain low-income countries. Our findings suggest that adiposity-related microbiota differences differ between low-to-middle-income compared to high-income countries.

  • Diagnostic performance of the Fibrosis-4 Index and Nonalcoholic Fatty Liver Disease Fibrosis Score in lean adults with nonalcoholic fatty liver disease

    This diagnostic study of adults in Asia evaluates the performance of 2 index scores in estimating clinical outcomes for individuals with nonalcoholic fatty liver disease.

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