• Motorised spiral enteroscopy safe in real-life and in patients with altered anatomy

    In a real-life setting, motorised spiral enteroscopy (MSE) was safe and effective to use in a large cohort of patients. Safety and feasibility was demonstrated.

  • Novel tool can reliably exclude submucosal invasion in colorectal polyps

    Endoscopists of varying experience reliably excluded submucosal invasion in large non-pedunculated colorectal polyps using a novel clinical decision support tool.

  • Filgotinib demonstrates long-term corticosteroid-sparing effects in patients with ulcerative colitis

    Corticosteroid-free remission was reached in more patients receiving filgotinib in the maintenance phase than placebo for moderately to severely active UC.

  • Serologic response to COVID-19 mRNA vaccine reduced in IBD patients on anti-TNFα

    Patients with IBS treated with anti-TNFα showed a reduced immune response to COVID-19 mRNA vaccines compared to IBD patients without anti-TNFα treatment and healthy controls.

  • APAAACI President Prof. Ruby Pawankar on the congress highlights 2021

    Conference Chair and APAAACI President Prof. Ruby Pawankar talks about the highlights of this year's APAAACI Conference. Prof. Pawankar shares her thoughts about allergy prevention, the challenges of the global pandemic and the impact of her research on the next generation.

  • Immunotherapy for allergen-related respiratory diseases

    Subcutaneous and sublingual immunotherapy (SCIT, SLIT) are the most common methods for controlling allergic rhinitis (AR). At this year's APAAACI Congress, Prof. M. Okano, MD, presented research on the safety, efficacy and adherence of the two treatment regimens.

  • Upadacitinib outperforms placebo in ulcerative colitis with inadequate response to biologics

    Superiority of upadacitinib over placebo as induction therapy for patients with moderately to severely active ulcerative colitis was observed.

  • COVID-19 vaccines: New concepts for high-risk patients

    Since the first anaphylactic reactions after injection of the COVID-19 vaccines, studies on side effects and severe allergic events have been ongoing worldwide. Now there are also first results on a successful premedication scheme and vaccination concepts for high-risk patients.

  • COVID-19 vaccine reactions: Emergency procedure

    Eight COVID-19 vaccines are licensed in the Philippines. Severe reactions to these and anaphylactic events occur very rarely. But to react early, an interdisciplinary team set up a concept for different risk groups.

  • Allergies and anaphylactic reactions: a growing problem of our time?

    The number of allergic reactions requiring treatment has risen sharply in recent years. Among triggering medications, antibiotics play a major role in daily practice. Yet, there is still a need for better documentation.

  • Allergies to food are on the increase - why is that?

    Food allergies are rising but it is still unclear why. This is also reflected in guidelines for the prevention and treatment of food allergies. Risk factors are being discussed again.

  • Chronic rhinosinusitis with nasal polyps in adults

    CRSwNP usually accompanies those affected throughout their lives. Multiple surgeries and long-term steroid therapy are the standard treatment. This can be extended by biologics use.

  • AD patients with stable disease fare equally well with a longer tralokinumab dose interval

    Clear or almost clear skin and mild or no itch symptoms were top predictors of maintained response to tralokinumab in moderate-to-severe AD.

  • Skin cancer detection apps disappoint in rare lesion recognition

    A British study showed that both a direct-to-consumer app and an app used for scientific purposes failed to recognise rare skin cancers.

  • Ligelizumab appears safe and effective in adolescents with CSU

    Ligelizumab for adolescents with chronic spontaneous urticaria, insufficiently controlled with antihistamines, did not raise new safety concerns.

  • Damaged skin: a potential transmission route for SARS-CoV-2?

    In different skin models, key receptors could be identified whose modulation can help in creating compromised-skin topicals against SARS-CoV-2 entry.

  • Headaches in children are often underestimated

    According to studies, more than two-thirds of schoolchildren have headaches on a regular basis. Around 20% of children and adolescents repeatedly miss lessons as a result.

  • Anti-OX40 antibody KHK4083 shows potential for long-term AD control

    The assessment of a novel anti-OX40 antibody resulted in substantial reductions in Eczema Area and Severity Index scores in a recent trial.

  • Antithrombotics in COVID-19 outpatients

    A study published in JAMA investigated whether adding antithrombotic therapy to placebo reduced major cardiopulmonary complications over a 45-day treatment period in COVID-19 outpatients.

  • Opioid receptor agonist benefits patients with itch-dominated AD

    For atopic dermatitis with less than 10% body surface area involvement, difelikefalin has exhibited significant efficacy in itch reduction.

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